Results 111 to 120 of about 3,320,190 (287)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Weight changes from early to middle adulthood and cardiometabolic multimorbidity later in life among middle-aged and older adults: a retrospective cohort study from the NHANES 1999-2018

Frontiers in Endocrinology
BackgroundWeight gain in adulthood can influence the development of diabetes and cardiovascular diseases. It is speculated that weight gain is related to cardiometabolic multimorbility (CMM).
Fayun Zhao, Qiang Zhao, Huandong Wang, Kun Wang, Shenke Kong, Peiyao Ma, Xin Wang   +6 more
doaj   +1 more source

Secular trends in body dimensions among young tennis players from 1992 to 2008 [PDF]

, 2013
Several studies have examined both physical characteristics and fitness of children and youth. The aim of the study was first, to find the tendency of changes in selected morphological characteristics of young male and female tennis players of various ...
Filipčič, Aleš, Filipčič, Tjaša, Leskošek, Bojan, Šarabon, Nejc   +3 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Self-reported weight change and diet quality in relation to metabolic syndrome among Korean cancer survivors: a cross-sectional study using the Korea National Health and Nutrition Examination Survey 2019–2021 [PDF]

Korean Journal of Community Nutrition
Objectives Using data from the 2019‒2021 Korea National Health and Nutrition Examination Survey, we examined the association between dietary quality and metabolic syndrome by self-reported weight change among adult Korean cancer survivors.
Hye Won Kim, Ji-Myung Kim
doaj   +1 more source

Polaron to molecule transition in a strongly imbalanced Fermi gas

, 2009
A single down spin Fermion with an attractive, zero range interaction with a Fermi sea of up-spin Fermions forms a polaronic quasiparticle. The associated quasiparticle weight vanishes beyond a critical strength of the attractive interaction, where a ...
G. V. Skorniakov, G. V. Skorniakov, M. Punk, P. T. Dumitrescu, R. P. Feynman, W. Zwerger   +5 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Weight Changes During Tuberculosis Treatment and Associated Factors: A Historical Cohort Study in Golestan Province, Iran (2020) [PDF]

مجله دانشگاه علوم پزشکی گرگان
Background and Objective: Tuberculosis (TB), caused by a bacterium called Mycobacterium TB, is the most prevalent infectious disease leading to mortality worldwide. Weight loss is frequently observed in TB patients at the time of diagnosis.
Mohammad Reza Honarvar, Mahsa Ghaffari, Naser Behnampour   +2 more
doaj  

The effects of sildenafil ciltrate on the lateral geniculate body of adult Wistar rats (Rattus norvegicus)- A histological study [PDF]

, 2010
The histological effect of oral administration of sildenafil citrate (Viagra), commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely the lateral geniculate body (LGB) of adult Wistar rat ...
Eweka, A, Eweka, AO
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source