Results 111 to 120 of about 514,621 (311)

EFFECT OF DIFFERENT FEEDING LEVELS ON PRODUCTIVE PERFORMANCE AND ECONOMIC FEASIBILITY OF PEKIN DUCKS IN KURDISTAN REGION OF IRAQ

open access: yesThe Iraqi Journal of Agricultural science
This study aimed to investigate the effect of different feeding levels of Alfalfa pellet ration (APR) on the productive performance and economic feasibility of Pekin ducks (Anas platyrhynchos). A total of 270 one-day-old ducklings were used.
Azad Sh. S. Al-Dabbagh   +1 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Effect of Sesbania Grandiflora (Agati) Supplementation on Weight Gain of Crossbred Jersey Heifer Calves

open access: yesInternational Journal of Economic Plants, 2021
An overarching factor that influences age at puberty in heifers is nutritional management during the preweaning and postweaning periods. The objective of this study was to evaluate supplementation of Sesbania grandiflora (Agati)as a legume forage ...
Periyasamy Vijayakumar   +4 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Food Prices and the Dynamics of Body Weight [PDF]

open access: yes
A popular policy option for addressing the growth in weight has has been the imposition of a “fat tax” on selected foods that are deemed to promote obesity.
Dana Goldman   +2 more
core  

The weight-inclusive vs. weight-normative approach to health: Evaluating the evidence for prioritizing well-being over weight [PDF]

open access: yes, 2014
Using an ethical lens, this review evaluates two methods of working within patient care and public health: the weight-normative approach (emphasis on weight and weight loss when defining health and well-being) and the weight-inclusive approach (emphasis ...
Shuman, E.   +13 more
core   +1 more source

AT1 receptor blockade alters nutritional and biometric development in obesity-resistant and obesity-prone rats submitted to a high fat diet

open access: yesFrontiers in Psychology, 2014
Obesity is a chronic metabolic condition with important public health implications associated with numerous co-morbidities including cardiovascular disease, insulin resistance, and hypertension.
Pauline M Smith   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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