Results 111 to 120 of about 1,716,637 (307)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Growth response of Heterobranchus longifilis fingerlings fed with varying levels of dietary freshwater mussel (Aspatharia sinuata) [PDF]
, 2005 A common bivalve: Freshwater mussel, Aspatharia sinuate was evaluated as a dietary protein supplement in the production diet for Heterobranchus longifilis fingerlings with mean body weight 8.34 plus or minus 10g reared in aquaria tanks.
Alatise, S.P. +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Pertumbuhan Anak Kambing Peranakan Etawah (PE) Sampai Umur 6 Bulan di Pedesaan
Jurnal Ilmiah Ilmu-Ilmu Peternakan, 2008 The research on the growth of Peranakan Etawah goat until six months-old during rainy and drought season was done in Petaling Jaya village Kecamatan Kumpeh Kabupaten Muaro Jambi. Ninety three Peranakan Etawah goats were used as sample based
Indra Sulaksana
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Fatores determinantes da retenção de peso no pós-parto: uma revisão da literatura
Cadernos de Saúde PúblicaEste trabalho constitui-se em uma revisão de literatura sobre fatores determinantes da retenção de peso em mulheres no pós-parto. Os resultados da revisão demonstraram que os principais fatores determinantes incluem o ganho de peso gestacional e a ...
Gilberto Kac
doaj
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Why the Poor Get Fat: Weight Gain and Economic Insecurity [PDF]
Something about being poor makes people fat. Though there are many possible explanations for the income-body weight gradient, we investigate a promising butlittle-studied hypothesis: that economic insecurity acts as an independent cause of weight gain ...
Christiana Stoddard +2 more
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source