Results 81 to 90 of about 1,716,637 (307)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Does Weight Gain Associated with Thiazolidinedione Use Negatively Affect Cardiometabolic Health?
Journal of Obesity & Metabolic Syndrome, 2017 Thiazolidinediones (TZDs) are oral anti-diabetic drugs that are peroxisome proliferator-activated receptor gamma (PPARγ) agonists and act as insulin sensitizers.
Ki Dong Ko, Kyoung Kon Kim, Kyu Rae Lee
doaj +1 more source
Sugar and Type 2 diabetes [PDF]
, 2016 Background: Consumption of sugar, specifically sugar-sweetened beverages, has been widely held responsible by the media for the global rise in Type 2 diabetes (T2DM).
Lean, Michael E.J., Te Morenga, Lisa
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Semina: Ciências Agrárias, 2018 The goal was to evaluate if feeding systems with or without milk or breed groups can improve carcass characteristics, the proportion of tissues and meat tenderness of feedlot goat kids.
Pedro Paulo Sobolow de Souza +7 more
doaj +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Performance of Braford steers grazing on cultivated pastures and fed or not fed an energy supplement
Revista Brasileira de Zootecnia, 2013 This experiment evaluated the performance of 84 Braford steers grazing on summer and winter cultivated pastures fed or not fed an energy-protein supplement. Steers were 10 months old and weighed, on average, 165 kg at the beginning of the trial.
Ricardo Zambarda Vaz +2 more
doaj
Prepregnancy body mass index, gestational weight gain, and birth weight in the BRISA cohort
Revista de Saúde Pública, 2018 OBJECTIVE To analyze the effects of maternal pre-pregnancy body mass index and weight gain during pregnancy on the baby's birth weight. METHODS We conducted a cross-sectional study with 5,024 mothers and their newborns using a Brazilian birth cohort ...
Raina Jansen Cutrim Propp Lima +7 more
doaj +1 more source
Changes in dietary patterns and body composition within 12 months of liver transplantation [PDF]
, 2016 Background: Cardiometabolic risk factors are increasing in liver transplant recipients (LTR). Influencing dietary factors have not been assessed. The aim of this observational study was to assess changes in weight, metabolic function, dietary intake and ...
Campbell, Katrina Louise +7 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source