Results 91 to 100 of about 558,138 (246)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Estimation of Cardiorespiratory Fitness Without Exercise Testing: Cross-Validation in Midlife and Older Women

open access: yesWomen's Health Reports, 2020
Background: Cardiorespiratory fitness (CRF) is associated with important health risk outcomes, including the development of Type 2 diabetes and cardiovascular disease. Measures of maximal or peak oxygen consumption (VO2) are the typical criterion methods
Jody L. Clasey   +4 more
doaj   +1 more source

Genetic aspects of calving, growth, and carcass traits in beef cattle [PDF]

open access: yes, 2003
The aim of this thesis was to learn more about the genetic background of calving, growth and carcass traits of beef cattle breeds in Sweden, and to assess the possibility of including calving traits and commercial carcass traits in the genetic evaluation.
Eriksson, Susanne
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

THE USE OF COLEMAN'S POWER INDICES TO INFORM THE CHOICE OF VOTING RULE WITH REFERENCE TO THE IMF GOVERNING BODY AND THE EU COUNCIL OF MINISTERS [PDF]

open access: yes
In his well known 1971 paper the mathematical sociologist James S. Coleman, proposed three measures of voting power : (1) "the power of a collectivity to act", (2) "the power to prevent action" and (3) "the power to initiate action".
Leech, Dennis
core  

Determinants of Faculty Gender Ratios Across Institutions and Departments [PDF]

open access: yes, 2000
Faculty gender ratios vary considerably across institutions, and past research (Tolbert and Oberfield 1991; Bach and Perrucci 1984) has shown that certain characteristics of institutions have a significant effect on these gender ratios. Understanding the
Rajeswaren, Anita Nimi
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Variogram investigation of covariance shape within longitudinal data with possible use of a krigeage technique as an interpolation tool: Sheep growth data as an example [PDF]

open access: yes, 2014
peer-reviewedMost quantitative traits considered in livestock evolve over time and several continuous functions have been proposed to model this change.
Chalh, A., El Gazzah, M.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Interrelation between body weights of sire, dam and their lambs at early stage of growth [PDF]

open access: yesBiotechnology in Animal Husbandry, 2020
Records of female lambs and their parents of the Mis sheep breed have used. All animals are approximately have weaned at 90 days of age. Descriptive statistics, paired sample test, paired differences, measures of association, correlations and regression ...
Caro-Petrović Violeta   +6 more
doaj  

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