Diagnostic sensitivity and specificity of metagenomic sequencing and qPCR for detection of viruses associated with bovine respiratory disease estimated using Bayesian latent class models. [PDF]
Donbraye E +10 more
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Evolution of Bovine Herpesvirus-1 infection prevalence and infection dynamics in Irish dairy herds following an IBR hyperimmunisation vaccination protocol. [PDF]
Duffy R +10 more
europepmc +1 more source
Non-neuronal sites of latency for alphaherpesviruses. [PDF]
Harrison KS.
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Bovine herpesvirus 1 (BoHV-1) causes respiratory infections and abortions in cattle, and is an important component of bovine respiratory disease complex, which causes a considerable economic loss worldwide. Several efforts have been made to produce safer and more effective vaccines.
Shafiqul I Chowdhury, Daniel B Paulsen
exaly +4 more sources
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Enhanced immunogenicity of a BoHV-1 gG-/tk- vaccine
VaccineBovine herpesvirus type 1 (BoHV-1) is a widespread respiratory infection that significantly impacts cattle health worldwide. To address this issue in China, we previously developed a novel double gene-deleted vaccine targeting gG and tk. In this study, we further evaluated the efficacy of this vaccine by challenging vaccinated cattle with a prevalent ...
Guoxing Liu, Aizhen Guo, Yingyu Chen
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Dynamics of natural bovine herpesvirus-1 (BoHV-1) infection in a dairy herd
In this study, natural cycling of BoHV-1 infection was investigated in two groups of dairy cattle containing 2120 head. Group 1 comprised 127 animals and they were monitored for BoHV-1 infection virologically and serologically in six consecutive sampling periods.
Ozkul, A., Gungor, A. Burak
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Rapid detection of BoHV-1 genomic DNA by loop-mediated isothermal amplification assay
Journal of Virological Methods, 2014Bovine herpes virus-1 (BoHV-1) is a serious viral pathogen of domestic and wild cattle. Herein, we report development of a new molecular diagnostic assay for rapid and sensitive detection of BoHV-1 utilizing the loop-mediated isothermal amplification (LAMP) technique.
Khaled Abdelrahman, H Soliman
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Evaluation of safety and efficacy of DNA vaccines against bovine herpesvirus-1 (BoHV-1) in calves [PDF]
Four DNA vaccines against BoHV-1 were evaluated for their efficacy in calves. Twelve animals were divided into four groups which were injected with four different DNA vaccines: pVAX-tgD (Vaccine A); pVAX-tgD co-immunised with pVAX-48CpG (Vaccine B); pVAX-UbiLacI-tgD-L (Vaccine C); pVAX-UbiLacI-tgD-L co-immunised with pVAX-48CpG (Vaccine D).
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Molecular detection of bovine herpesvirus 1 (BoHV-1) in cattle in Serbia
The presence of bovine herpesvirus 1 (BoHV-1) was examined in 110 samples of bovine nasal swabs collected between October 2007 and November 2015. BoHV-1 was detected in four samples by virus isolation and polymerase chain reaction (PCR). The phylogenetic analysis of glycoprotein B (gB) gene nucleotide sequences of all four BoHV-1 strains showed that ...
Nišavić, Jakov +4 more
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DEVELOPMENT OF A CRISPR-BASED ANTIVIRAL SYSTEM AGAINST BOHV-1
Cytotherapy, 2021Background Bovine Herpesvirus type 1 (BoHV-1) infection has no cure and infected animals become lifelong carriers, greatly impacting health and productivity of herds worldwide. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas (CRISPR associated) tool has been widely explored for the development of antiviral strategies due to ...
VGF Pastre, FRO de Barros
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