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The role of sheep in the epidemiology of Bovine alphaherpesvirus 1 (BoHV-1)

Preventive Veterinary Medicine, 2020
Bovine alphaherpesvirus 1 (BoHV-1) as a cusative agent for some diseases in cattle infects sheep and goat; and it is believed that these animals may be reservoir host for this virus. Thus, BoHV-1 infection in sheep and goat should be considerd when there is a program for control and eradication of this virus in cattle.
Mahdi, Pourmahdi Borujeni   +3 more
openaire   +2 more sources

A derivative of bovine herpesvirus 1 (BoHV-1) UL3.5 lacking the last forty amino acids inhibits replication of BoHV-1

Archives of Virology, 2004
Bovine herpesvirus 1 (BoHV-1) UL3.5 is a tegument protein that interacts with BoHV-1 alpha-transinducing factor alphaBTIF). In this report, we show that a truncated UL3.5 lacking the last 40 amino acids (C40UL3.5) inhibited replication of BoHV-1. Stable expression of C40UL3.5 in MDBK cells inhibited replication of BoHV-1 300- to 500-fold in plaque ...
N, Lam, G, Letchworth
openaire   +2 more sources

Prevalence of exposure to bovine viral diarrhoea virus (BVDV) and bovine herpesvirus-1 (BoHV-1) in Irish dairy herds [PDF]

open access: yesResearch in Veterinary Science, 2015
Bovine viral diarrhoea virus (BVDV) and bovine herpesvirus 1 (BoHV-1) are contagious bovine viral agents. The objectives of this study were to use quarterly bulk milk and ‘spot’ testing of unvaccinated youngstock to establish the national prevalence of ...
R G Sayers, N Byrne
exaly   +2 more sources

Characterization of BoHV-1 gE envelope glycoprotein mimotopes obtained by phage display

Veterinary Microbiology, 2004
A phage-displayed peptide library was screened using four mAbs directed against bovine herpesvirus 1 (BoHV-1) gE glycoprotein to identify peptides mimicking this glycoprotein. The selected mimotopes allowed us to characterize the epitopes corresponding to the mAbs as continuous and proteinic and to consider using these peptides in further studies.
D, Lehmann, R, Sodoyer, S, Leterme
openaire   +2 more sources

Development and evaluation of recombinant gD protein based ELISA for sero-surveillance of BoHV-1 in India

Biologicals, 2023
Bovine herpes virus-1 (BoHV-1) is responsible for production losses through decreased milk yields, abortions, infertility, and trade restrictions in the bovine population. The disease is endemic in many countries including India. As the virus harbors a unique feature of latency animals once infected with the virus remain sero-positive for lifetime and ...
Sushmita Nautiyal   +9 more
openaire   +2 more sources

BoHV-1 UL3 inhibits RLR signaling response by degrading MAVS

Veterinary Microbiology
Bovine herpesvirus 1 (BoHV-1) infection can lead to host immunosuppression, and its tegument proteins play a critical role in suppressing antiviral immune responses. However, the mechanisms by which BoHV-1 tegument proteins modulate the RLR signaling pathway and influence the replication of bovine RNA viruses remain poorly understood.
Yanan, Xu   +3 more
openaire   +2 more sources

The Antiviral Effects of Sodium Phenylbutyrate Against BoHV-1 Infection In Vitro

Letters in Drug Design & Discovery, 2019
Introduction: The alteration of histone acetylation is a known mechanism to regulate gene expression, and thereby affecting various cellular processes. Histone deacetylases (HDACs) are known to regulate histone acetylation by removal of the acetyl group from lysines.
Xinye Chen, Guoqiang Zhu, Liqian Zhu
openaire   +1 more source

Maternal antibody transfer efficiency: The impact of M. bovis-BoHV-1 combined vaccine

Virology
Bovine respiratory disease (BRD) is a complex and one of the most costly diseases caused by multiple bacterial and viral infections. Cattle of almost all ages are susceptible to BRD, with young day-old newborn calves being the most at risk. The ability of newborn calves to acquire passive immunity from milk, appears to be a critical issue in ...
Sen Zhang   +3 more
openaire   +2 more sources

Enhanced immune response with baculovirus-expressed BoHV-1 glycoprotein D in vaccine development

The Veterinary Journal
Bovine herpesvirus 1 (BoHV-1), a significant pathogen in the alpha-herpesvirus subfamily, primarily infects cattle and causes the upper respiratory disease known as infectious bovine rhinotracheitis (IBR). In silico studies evaluated the BoHV-1 D protein to be non-allergenic, non-toxic, and highly antigenic, highlighting its potential as an antigen for
Nguyen-Thanh, Hoa   +7 more
openaire   +2 more sources

The Antiviral Effects of Harmine Against BoHV-1 Infection In Vitro

Letters in Drug Design & Discovery, 2017
Xinyi Jiang   +5 more
openaire   +1 more source

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