Results 161 to 170 of about 70,387 (299)

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source

Bridging Green Chemistry and Circular Economy: A Pathway to Sustainable Polyester Plastics Through Feedstock, Synthesis, and Waste Upcycling

Advanced Science, EarlyView.
This review summarizes green and low‐carbon strategies throughout the entire life cycle of polyester plastics, including sustainable monomer synthesis, optimization polymerization, efficient recycling, and advanced upcycling technologies. The synergistic implementation of these strategies is expected to significantly promote the development of a ...
Jinzhou Li, Junliang Chen, Yingbing Zhang, Li Wang, Pin Gao, Jianping Yang   +5 more
wiley   +1 more source

Earth-mass planets with He atmospheres in the habitable zone of Sun-like stars. [PDF]

Nat Astron
Lammer H, Scherf M, Erkaev NV, Kubyshkina D, Gorbunova KD, Fossati L, Woitke P.   +6 more
europepmc   +1 more source

Molecular Dynamics Simulation of Natural Gas Liquefied LNG Boil-Off

Acta Scientific Medical Sciences, 2019
Mesli Fouzia, Missoum Noureddine, Ghalem Saïd   +2 more
openaire   +1 more source

Design manual: Oxygen Thermal Test Article (OTTA) [PDF]

The characteristics of a cryogenic tank for storing liquid hydrogen, nitrogen, oxygen, methane, or helium for an extended period of time with minimum losses are discussed.
Baese, C. L., Chronic, W. L., Conder, R. L.   +2 more
core   +1 more source

Non‐Equilibrium Synthesis Methods to Create Metastable and High‐Entropy Nanomaterials

Advanced Science, EarlyView.
ABSTRACT Stabilizing multiple elements within a single phase enables the creation of advanced materials with exceptional properties arising from their complex composition. However, under equilibrium conditions, the Hume–Rothery rules impose strict limitations on solid‐state miscibility, restricting combinations of elements with mismatched crystal ...
Shuo Liu, Chaochao Dun, Jeffrey J. Urban, Mark T. Swihart   +3 more
wiley   +1 more source

Core-envelope miscibility in sub-Neptunes and super-Earths. [PDF]

Nature
Gilmore T, Stixrude L.
europepmc   +1 more source

Combining Electrochemical Reduction with Biosynthesis for Directed Conversion of CO2 into a Library of C3 Chemicals

Advanced Science, EarlyView.
In the H‐type electrolytic cell, carbon dioxide is reduced to acetic acid via electro‐microbial catalysis. The simply processed acetic acid is further converted through biological fermentation into high‐value‐added products, including acrylic acid, L‐lactic acid, and β‐alanine.
Kaixing Xiao, Shanquan Liang, Xujun Zhao, Zhiyao Peng, Ruoshi Luo, Jikai Zong, Ling Zhou, Yude Su, Dan Wang   +8 more
wiley   +1 more source

An Economical and Efficient Helium Recovery System for Vibration-Sensitive Applications. [PDF]

ACS Meas Sci Au
Yin Z, Bi L, Shi Y, Li S.
europepmc   +1 more source

Interfacial Engineering in Rare‐Earth Oxide/ZnO Heterojunctions for High‐Performance Trimethylamine Sensing and Fish Freshness Monitoring

Advanced Science, EarlyView.
This study realizes superior gas sensing performance via Yb2O3/ZnO heterojunction design, achieving highly sensitive/selective trimethylamine detection at room temperature while elucidating the intrinsic sensing mechanism. This innovation is applied to reliable real‐time fish freshness monitoring, paving a feasible way for translating advanced material
Junxi Cheng, Chang Liu, Miaomiao Liu, Qihua Sun, Jun Sun, Zhaofeng Wu   +5 more
wiley   +1 more source