Results 251 to 260 of about 865,620 (376)

Techno‐Economic Analysis of Polylactic Acid from Corn Stover: Understanding Uncertainty and Variability via Artificial Intelligence Tools

open access: yesAdvanced Sustainable Systems, EarlyView.
This study analyses the uncertainty and variability existing in the economic performance of polylactic acid (PLA) production, via integrating techno‐economic analysis with process models and Monte Carlo simulation enabled by artificial intelligence. The results show that the minimum selling price varies from $2,107 to $3076/t PLA.
Yinqiao Wang   +5 more
wiley   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang   +8 more
wiley   +1 more source

Prediction of SF<sub>6</sub> Replacement Gases Based on Machine Learning. [PDF]

open access: yesACS Omega
Ding G   +6 more
europepmc   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Combined computational, rational, and empirical design of boiling-resistant keratinase. [PDF]

open access: yesAppl Environ Microbiol
Yang Y   +10 more
europepmc   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

Active Tablet Coating with Amorphous Solid Dispersion of Ibuprofen-HPMCAS from Organic Solution. [PDF]

open access: yesPharmaceutics
Raciborska L   +4 more
europepmc   +1 more source

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