Results 191 to 200 of about 3,586 (258)

Investigating the prevalence of class 1, 2, and 3 integrons in carbapenem-resistant Acinetobacter baumannii isolated from burn wound infections. [PDF]

Sci Rep
Emamgholitabar Malekshah F, Gholami M, Pahlavanian M, Goli HR.   +3 more
europepmc   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

Edible Insects as an Alternative Source of Nutrients: Benefits, Risks, and the Future of Entomophagy in Europe-A Narrative Review. [PDF]

Foods
Jankowski WM, Przychodniak D, Gromek W, Majsiak E, Kurowski M.   +4 more
europepmc   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

COP 28: Challenge of coping with climate crisis. [PDF]

Innovation (Camb)
Jiang T, He X, Su B, Havea PH, Wei K, Kundzewicz ZW, Liu D.   +6 more
europepmc   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source

Exploring the life stories of young adult men in prison with a history of dual harm. [PDF]

Front Psychiatry
Thurston L, Slade K, Blagden N, Baguley T, Vinter LP.   +4 more
europepmc   +1 more source

Sudan: from a forgotten war to an abandoned healthcare system. [PDF]

BMJ Glob Health
Elamin A, Abdullah S, ElAbbadi A, Abdellah A, Hakim A, Wagiallah N, Ansah JP.   +6 more
europepmc   +1 more source

Research Progress in Chitin/Chitosan-Based Biomass Adhesives: Extraction Processes, Composite and Chemical Modification. [PDF]

Polymers (Basel)
Luo Y, Zhang Z, Zuo J, Zhang L.
europepmc   +1 more source