Results 51 to 60 of about 1,786,461 (344)
Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]
Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul +9 more
core +3 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Multiband multi-echo simultaneous ASL/BOLD for task-induced functional MRI. [PDF]
Typical simultaneous blood oxygenation-level dependent (BOLD) and arterial spin labeling (ASL) sequences acquire two echoes, one perfusion-sensitive and one BOLD-sensitive. However, for ASL, spatial resolution and brain coverage are limited due to the T1
Alexander D Cohen +2 more
doaj +1 more source
Elastic Gateway Functional Safety Architecture and Deployment: A Case Study
The automotive industry has started its transformation towards Software-Defined Vehicles. This transformation is driven by the rise of the number of vehicle features, the high complexity of these features and their constraining availability requirements ...
Abdoul Aziz Kane +5 more
doaj +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Novel Algorithms Based on Majorization Minimization for Nonnegative Matrix Factorization
Matrix decomposition is ubiquitous and has applications in various fields like speech processing, data mining and image processing to name a few. Under matrix decomposition, nonnegative matrix factorization is used to decompose a nonnegative matrix into ...
R. Jyothi, Prabhu Babu, Rajendar Bahl
doaj +1 more source
Hardware Acceleration of a Generalized Fast 2-D Convolution Method for Deep Neural Networks
The hardware acceleration of Deep Neural Networks (DNN) is a highly effective and viable solution for running them on mobile devices. The power of DNNs is now available at the edge in a compact and power-efficient form factor with the aid of hardware ...
Anaam Ansari, Tokunbo Ogunfunmi
doaj +1 more source
Experimental Design Modulates Variance in BOLD Activation: The Variance Design General Linear Model
Typical fMRI studies have focused on either the mean trend in the blood-oxygen-level-dependent (BOLD) time course or functional connectivity (FC). However, other statistics of the neuroimaging data may contain important information.
Gaut, Garren +3 more
core +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source

