Results 51 to 60 of about 714,094 (293)
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openaire +4 more sources
Noncanonical spike-related BOLD responses in focal epilepsy [PDF]
Till now, most studies of the Blood Oxygen Level-Dependent (BOLD) response to interictal epileptic discharges (IED) have assumed that its time course matches closely to that of brief physiological stimuli, commonly called the canonical event-related ...
Lemieux, L. +11 more
core
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
We propose a noise adaptive Kalman filter for joint polarization tracking and channel equalization using cascaded covariance matching. With the process noise covariance (Q) and the measurement noise covariance (R) estimated in a cascaded manner, the ...
Qun Zhang +5 more
doaj +1 more source
Visual Relationship Detection With Visual-Linguistic Knowledge From Multimodal Representations
Visual relationship detection aims to reason over relationships among salient objects in images, which has drawn increasing attention over the past few years.
Meng-Jiun Chiou +2 more
doaj +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Community health workers: developing roles in public health dementia efforts in the United States
Community Health Workers (CHWs) are a growing part of the healthcare workforce. Trusted in their communities, CHWs can provide essential health education and connection with culturally responsive health and support resources and programs.
Elma Johnson +14 more
doaj +1 more source
This research deals with the investigation of electrocoagulation (EC) treatment of wastewater from a dairy plant using aluminum electrodes. Electrolysis time, pH, current density and distance between electrodes were considered to assess the removal ...
Gerson de Freitas Silva Valente +2 more
doaj +1 more source

