Results 51 to 60 of about 1,786,461 (344)

Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]

open access: yes, 2015
Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul   +9 more
core   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Multiband multi-echo simultaneous ASL/BOLD for task-induced functional MRI. [PDF]

open access: yesPLoS ONE, 2018
Typical simultaneous blood oxygenation-level dependent (BOLD) and arterial spin labeling (ASL) sequences acquire two echoes, one perfusion-sensitive and one BOLD-sensitive. However, for ASL, spatial resolution and brain coverage are limited due to the T1
Alexander D Cohen   +2 more
doaj   +1 more source

Elastic Gateway Functional Safety Architecture and Deployment: A Case Study

open access: yesIEEE Access, 2022
The automotive industry has started its transformation towards Software-Defined Vehicles. This transformation is driven by the rise of the number of vehicle features, the high complexity of these features and their constraining availability requirements ...
Abdoul Aziz Kane   +5 more
doaj   +1 more source

James Hogg [PDF]

open access: yes, 2005
No abstract ...
Bold, Valentina
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Novel Algorithms Based on Majorization Minimization for Nonnegative Matrix Factorization

open access: yesIEEE Access, 2019
Matrix decomposition is ubiquitous and has applications in various fields like speech processing, data mining and image processing to name a few. Under matrix decomposition, nonnegative matrix factorization is used to decompose a nonnegative matrix into ...
R. Jyothi, Prabhu Babu, Rajendar Bahl
doaj   +1 more source

Hardware Acceleration of a Generalized Fast 2-D Convolution Method for Deep Neural Networks

open access: yesIEEE Access, 2022
The hardware acceleration of Deep Neural Networks (DNN) is a highly effective and viable solution for running them on mobile devices. The power of DNNs is now available at the edge in a compact and power-efficient form factor with the aid of hardware ...
Anaam Ansari, Tokunbo Ogunfunmi
doaj   +1 more source

Experimental Design Modulates Variance in BOLD Activation: The Variance Design General Linear Model

open access: yes, 2018
Typical fMRI studies have focused on either the mean trend in the blood-oxygen-level-dependent (BOLD) time course or functional connectivity (FC). However, other statistics of the neuroimaging data may contain important information.
Gaut, Garren   +3 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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