Results 21 to 30 of about 104,844 (248)
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Claustrum Involvement in New Onset Refractory Status Epilepticus: A Systematic Review
ABSTRACT The claustrum sign is a distinctive neuroimaging finding characterized by bilateral T2/FLAIR hyperintensity of the claustrum, one of the most interconnected regions of the human brain. It was first described in new‐onset refractory status epilepticus (NORSE) and febrile infection–related epilepsy syndrome (FIRES).
Margherita Burani +5 more
wiley +1 more source
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco +7 more
wiley +1 more source
Osservazioni paleografiche su due papiri greci conservati all’Archiginnasio di Bologna
The essay presents a palaeographical analysis and description of two fragments of Greek papyrus (2nd and 3rd centuries AD), that are preserved at the Archiginnasio Library in Bologna. The two fragments (entirely reproduced) had not yet been edited, hence
Sandro Bertelli
doaj +1 more source
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà +15 more
wiley +1 more source
Precision Switching and Coupled Motion in a [3]Rotaxane Molecular Machine
A [3]rotaxane, composed by two crown ether macrocycles and an axle presenting three recognition sites, is operated through both chemical and electrochemical stimuli. The position of the macrocycles is precisely controlled by sequential stimulation and the processes are fully reversible. The characterization of the system revealed the macrocycles affect
Leonardo Andreoni +3 more
wiley +2 more sources
Giacomo Lercaro’s arrival in Bologna in the spring of 1952 and his appointment as cardinal the following year opened a 15-year period in which the Emilian city was at the center of important initiatives that gained notoriety both nationally and ...
Giovanni Bellucci
doaj +1 more source
Modification of geopolymer surface with a silane coupling agent containing quaternary ammonium group enables the development of dual‐functioning ion exchanger for both cations and anions. In the present study, the performance of this material was demonstrated for the uptake of ammonium and nitrate from water.
Yangmei Yu +7 more
wiley +1 more source
Strong Coupling in all‐Polymer Planar Microcavities
Strong Coupling has been achieved in an all‐polymer microcavity with dielectric contrast Δn = 0.33 doped with TDBC. A Rabi splitting of 39 meV has been measured opening novel perspectives for polymer photonics. ABSTRACT In this work, strong coupling effect is observed in all‐polymer planar microcavities incorporating TDBC J‐aggregates dispersed into ...
Daniela Di Fonzo +5 more
wiley +1 more source

