Results 81 to 90 of about 6,036 (256)

IMACulate(DE3), an E. coli Strain for High Purity His‐Tagged Protein Purifications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Immobilised Metal Affinity Chromatography (IMAC) is widely used to purify his‐tagged recombinant proteins from Escherichia coli. However, endogenous contaminants with histidine clusters, such as GFAT and PDH E1 proteins, are often co‐purified with the target protein.
Jia Q. Truong, Dingyi Yu, Nan Hao, Chris Langendorf, Keith. E. Shearwin, Jessica K. Holien   +5 more
wiley   +1 more source

Circular Economy in the Healthcare Industry: Developing a Circularity Assessment Tool for Complex Medical Devices

Business Strategy and the Environment, EarlyView.
ABSTRACT As the circular economy transition gains traction in the healthcare sector, extending the lifespan of complex medical devices has become a key priority, given their high cost and the challenges associated with their technological sophistication.
Tetiana Shevchenko, Lauren Durivault, Meisam Ranjbari, Zahra Shams Esfandabadi, Bernard Yannou, Robert Heidsieck, Michael Saidani, Ghada Bouillass   +7 more
wiley   +1 more source

Platform Thinking as a Catalyst for Circular Innovation in Low‐ and Medium‐Tech Industries

Business Strategy and the Environment, EarlyView.
ABSTRACT Growing pressures to replace linear with circular models challenge organisations to innovate continuously and to absorb new knowledge. While platform thinking has been examined as an enabler of innovation in high‐tech industries, its relevance in low‐ and medium‐tech industries, like construction, remains underexplored.
Julia Köhler, Sönnich Dahl Sönnichsen, Philip Beske‐Janssen, Christian Thuesen   +3 more
wiley   +1 more source

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

Chemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias, Aleen Khoury, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich‐Wright   +9 more
wiley   +1 more source

Integrating robotic systems in underground roof support machine

Journal of Industrial Safety
Traditionally, the roof bolting process is performed manually by skilled workers, which is time-consuming and labor-intensive. This often exposes human operators to several risks.
Peter Kolapo, Steven Schafrik, Hejia Zhang, Stefanos Nikolaidis, Zach Agioutantis   +4 more
doaj   +1 more source

Synergies and Trade‐Offs in Circular Economy and Community Development Nexus: Pathways to Local Sustainability

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Recent scholarship shows growing interest in the circular economy (CE) approach, which promotes resource‐efficient, community‐friendly activities. However, scientific evidence is still needed on the synergies and trade‐offs between CE and community development (CD).
Michael Odei Erdiaw‐Kwasie, Matthew Abunyewah, Kerstin Zander, Patrick Arhin, Amila Kasun Sampath Udage Kankanamge, Walter Leal Filho, Khorshed Alam   +6 more
wiley   +1 more source

Review and prospects of shear test of bolted rock joints

Deep Underground Science and Engineering, EarlyView.
The laboratory shear test equipment, test method, and numerical simulation of bolted rock joints were summarized. The shortcomings and limitations of the current research were analyzed, and the research prospects were proposed. Abstract Rock bolting is a critical approach in geotechnical engineering for supporting weak rocks.
Shulin Ren, Fan Yang, Manchao He, Yong Yuan, Zhigang Tao   +4 more
wiley   +1 more source

Shear behavior of bolt–grout interfaces under constant normal stiffness: Influence of grout strength and thickness

Deep Underground Science and Engineering, EarlyView.
The effects of grout strength and thickness on the shear behavior of bolt–grout interfaces (BGI) under constant normal stiffness conditions are investigated. Shear strength, failure modes, and acoustic emission characteristics are examined. The findings reveal that grout strength exerts a significantly greater influence on BGI shear strength and ...
Sunhao Zhang, Dongqi Shang, Yujing Jiang, Jinge Zhang, Hongbin Chen, Tianqi Jiang   +5 more
wiley   +1 more source

Multiple injection techniques to stimulate complex fracture networks in coal reservoirs: A case study on gas disaster reduction of subsurface coal mine in southwest China

Deep Underground Science and Engineering, EarlyView.
An experimental device for physical simulation of hydraulic fracturing, comprising: a load‐bearing mechanism with multiple interconnected plates that collectively form an sample chamber; a load‐generating mechanisms, with multiple load‐generating mechanisms arranged within the experimental chamber.
Delei Shang, Farui Shi, Jun Lu, Minghui Li, Cunbao Li, Heping Xie   +5 more
wiley   +1 more source

Modeling and experimental validation of bolt–grout bond–slip behavior for deep underground excavation support

Deep Underground Science and Engineering, EarlyView.
A novel shear‐lag model, validated by pull‐out tests, incorporates a constant bond stress stage to predict the complete load–displacement response of grouted rock bolts, providing a new tool for optimizing anchorage length and material toughness in deep underground engineering. Abstract The stability of rock masses in deep underground excavations, such
Wenhui Bian, Xiaohui He, Kexue Wang, Yufei Wu, Guoxin Wang, Shaochen Zhang, Jun Yang   +6 more
wiley   +1 more source