Results 31 to 40 of about 81,644 (285)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Introduktion till Fides et ratio

open access: yes, 1999
Introduktion till påven Johannes Paulus II:s encyklika Fides et ratio om förhållandet mellan religiös tro och det mänskliga förnuftet, utgiven i svensk översättning av Anders Piltz.
Jonsson, Ulf,
core   +6 more sources

Methodological issues of good faith (bona fides) in the roman law [PDF]

open access: yes, 2009
Статья посвящена проблеме методологических основ исследования концепции добросовестности. Современная концепция добросовестности берет свое начало из максим и других правовых правил римского права.
Шаркова, І.М.
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Hierarchia społeczna i categorie prave. Fides i bona fides

open access: yes, 2015
It is a common misconception that fides and bona fides are ethical principles with changeable content, shaped by the development of social and moral values.
FIORI, ROBERTO, Fiori, R
core   +1 more source

Investigating the Routine Dispatch Tasks Performed by Police Officers

open access: yesSafety, 2020
Police officers perform a variety of physical tasks that can range from deskwork to chasing down fleeing suspects on foot. If not sufficiently prepared these tasks can lead to an increased risk of injury or task failure.
Robin Orr   +4 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Bona fides, uberrima fides e boa-fé: transição conceitual e função estruturante no contrato de seguro [PDF]

open access: yes, 2022
A boa-fé apresenta especial significado no contrato de seguro. Daí a justificativa para o reconhecimento da sua natureza uberrima fides, a exigir, dos contratantes, que observem a máxima boa-fé ou a “mais estrita boa-fé e veracidade” na formação e ...
Petersen, Luiza Linhares Moreira
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Biblioteka klasztorna SS. Karmelitanek Bosych w Łodzi [PDF]

open access: yes, 2005
Poprawiona wersja artykułu zamieszczonego w: "Fides", 2002, nr
Łabiszewska, Irena
core  

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