Results 181 to 190 of about 1,277,787 (315)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Effect of Different Specimen Preparation Methods on Dentin Shear Bond Strength: Polyethylene Tubes vs Jig System. [PDF]

J Adhes Dent
Balaban Karakaş S, Karakaş M, Oğuz AM, Arısu HD.   +3 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Theoretical Investigation on the Mechanism of Ni⁰(enolate)-Ate Complex-Catalyzed C(sp²)-F Bond Activation and the Origin of Alkali Metal Cations Modulating Enantioselectivity. [PDF]

JACS Au
You XX, Zhong RL, Su ZM.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Bonds, Jammed Bonds

CFA Institute Magazine, 2017
openaire   +2 more sources

Bond of security for H. L. Dickinson

Bond of security for H. L. Dickinson as Auditor of Public Accounts, Territory of New Mexico, Santa Fe. Also signed by Calvin D. Scofield, James A. Donavant, joint authors. Witnessed by William Watts Hart Davis.

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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Effect of Fluorescent Adhesives on Visibility and Tooth Enamel Surface Properties After Debonding: A Systematic Review and Meta-Analysis. [PDF]

Clin Exp Dent Res
Omidkhoda M, Bardideh E, Nowabadi A, Entezari M.   +3 more
europepmc   +1 more source

Bond for license to trade with Comanches

Bond for license, Juan Bautista Lopez and James Conklin to trade with the Comanches. In the handwriting of James S. Calhoun, Superintendent of Indian Affairs, Santa Fe. Also signed by James Conklin. Witnessed by M. Ashurst.

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