Results 191 to 200 of about 1,277,787 (315)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Comparative analysis of heat impacts on bond strength and failure modes of calcium silicate- and epoxy resin-based sealers. [PDF]

BMC Oral Health
Kandil NM, Elashiry MM, Wong B, Elgendy AA.   +3 more
europepmc   +1 more source

Bond for license for Antoine Leroux

Abiquiu, New Mexico, bond for license to trade with the Comanches for Antoine Leroux, in the handwriting of James S. Calhoun. Not to trade in spirits, fire arms, lead, powder or munitions. Cost of contract, payment. Also signed by Jose Antonio ? and Juan

core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Heritage Society (Houston)

Transcribed text for a receipt from Thomas Bond to William M.

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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Composite repair bond strength to zirconia, resin matrix CAD/CAM ceramic, and PMMA-based CAD/CAM polymer after different conditioning protocols: an in vitro investigation. [PDF]

BMC Oral Health
Janson M, Schoppmeier CM, Liebermann A.
europepmc   +1 more source

Bond for license to trade with the Comanches

Santa Fe, bond for license to trade with the Comanches for William H. Moore. Also signed by William S. Messervy and James J. Webb. Witnessed by Wm. E. Love.

core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Mechanistic Elucidation of BBOX-Catalyzed Hydroxylation and THP-Induced Oxidative Rearrangement via QM/MM Calculations. [PDF]

Molecules
Ruan Z, Li H, Liu Y, Zhang X, Li X.
europepmc   +1 more source