Results 71 to 80 of about 3,548,015 (356)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Soaring debt levels and the crisis in Greece has sharpened the focus on fiscal sustainability among eurozone members. The European Union has to tackle high debt levels in vulnerable states which are compounded by a hike in risk premiums on government ...
Jacques Delpla, Jakob von Weizsäcker
core +1 more source
Bond-Bending and Bond-Stretching Phonons in Ferromagnetic La_0.7Sr_0.3MnO_3
, 2005 Longitudinal optical phonons with oxygen character were measured in La_0.7Sr_0.3MnO_3 by inelastic neutron scattering in the (1 0 0) cubic direction and results were compared with shell model predictions.
D. Reznik, W. Reichardt, W. Reichardt
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
GENEZIS OF LEGAL REGULATION OF CREDIT RELATIONS IN THE CONDITIONS OF TRANSITIVE ECONOMY OF UKRAINE
Фінансово-кредитна діяльність: проблеми теорії та практики, 2019 The purpose of the paper is to analyze the genesis of credit legal relationship as the notion in Civil law as well as historical transformations of its legal regulation at the different stages of Ukraine’s development.
Yevgenia Tupitska +2 more
doaj +1 more source
Australasian Orthodontic Journal, 1994 Abstract The advantages of indirect bonding have heen recognised for more than twenty years. However the technique has not gained widespread acceptance as an alternative to conventional direct honding. Reports of difficulty in achieving adequate isolation of posterior teeth and prohlems with resin flash and low hond strength may explain ...
openaire +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Proceedings, 2018 Loadbearing sandwich panels used as wall elements are a promising development since they combine structural and energy efficiency. Composite behaviour needs to be ensured so that the sandwich panel works as one element under a flexural load (meaning that
Jolien Vervloet +5 more
doaj +1 more source