Results 71 to 80 of about 3,541,930 (355)
Soaring debt levels and the crisis in Greece has sharpened the focus on fiscal sustainability among eurozone members. The European Union has to tackle high debt levels in vulnerable states which are compounded by a hike in risk premiums on government ...
Jacques Delpla, Jakob von Weizsäcker
core +1 more source
Fair Deals for Watershed Services: Lessons from a Multi-country Action-learning Project [PDF]
Payments for ecosystem services make good sense. In the case of watershed ecosystems, downstream beneficiaries of wise upstream land and water stewardship should compensate these upstream stewards.
Ivan Bond, James Mayers
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The paper presents the results of experimental investigations performed by the authors on the casting position factor. It was proved that at the height of reinforced concrete elements there are different bond conditions.
Dybeł Piotr, Furtak Kazimierz
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Abstract The advantages of indirect bonding have heen recognised for more than twenty years. However the technique has not gained widespread acceptance as an alternative to conventional direct honding. Reports of difficulty in achieving adequate isolation of posterior teeth and prohlems with resin flash and low hond strength may explain ...
openaire +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Methodology for Testing Rebar-Concrete Bond in Specimens from Decommissioned Structures
Mimicking natural deterioration in accelerated tests is challenging; a highly relevant alternative option is to use deteriorated specimens from decommissioned structures.
Karin Lundgren +2 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
GENEZIS OF LEGAL REGULATION OF CREDIT RELATIONS IN THE CONDITIONS OF TRANSITIVE ECONOMY OF UKRAINE
The purpose of the paper is to analyze the genesis of credit legal relationship as the notion in Civil law as well as historical transformations of its legal regulation at the different stages of Ukraine’s development.
Yevgenia Tupitska +2 more
doaj +1 more source

