Results 51 to 60 of about 4,638,821 (229)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A REVIEW OF BOND BEHAVIOR OF GLASS FIBER REINFORCED POLYMER BARS WITH CONCRETE

open access: yesJournal of Engineering and Sustainable Development, 2019
One of the most serious problems of reinforced concrete structures is corrosion of embedded reinforcing steel bars especially in aggressive environments.
Mohammed Hashim Mohammed
doaj  

Bond Behavior Between Steel Bar and Reactive Powder Concrete Under Repeated Loading

open access: yesBuildings
To investigate the influence of repeated loading on the bond behavior between steel bars and reactive powder concrete (RPC), this study conducted repeated loading tests on eight beam specimens and one static loading test as a control.
Dewen Zhang   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Numerical Investigation of the Bond–Slip Mechanism Between Deformed CFRP Bars and Ultra-High Performance Concrete

open access: yesApplied Sciences
To further investigate the bond behavior between carbon fiber-reinforced polymer (CFRP) bars and ultra-high-performance concrete (UHPC) under monotonic loading, a finite element model was established in ABAQUS based on existing experimental data.
Junling Jiang, Nachuan Liu, Changren Ke
doaj   +1 more source

Effect of Surface Treatment on Durability of GFRP Reinforced Aluminum Structure under Hygrothermal Environment

open access: yesJournal of Aeronautical Materials, 2018
The aluminum alloy surface was treated through three different processes. The bonding strength of GFRP-aluminum under hygrothermal environment with different surface treatments was tested and was arranged with the order of anodizing > silane coupling ...
YU Zhouhui, ZHAO Peizhong, HU Fangyou
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Texas Bond Review Board Annual Report

open access: yes, 2021
This report describes states financial in fiscal 2021, issuance cost, private activity bond and 86th legislature session, This report concludes with seven appendices.
Texas Bond Review Board
core  

Empirical Effective Strain Model for CFRP Plates Bonded to Concrete Using the Externally Bonded Reinforcement on the Grooves

open access: yesApplied Sciences
Externally bonded reinforcement (EBR) using fiber reinforced polymer (FRP) is one of the most widely used techniques for strengthening reinforced concrete (RC) structures.
Sangwon Ji   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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