Results 31 to 40 of about 2,347,040 (191)

Traditional Versus Customized CAD/CAM Rapid Palatal Expanders in Growing Patients: A Pilot Exploratory Prospective Non-Randomized Clinical Study

Applied Sciences
Background: Rapid palatal expansion (RPE) is the gold standard for maxillary deficiency in growing patients. Conventional soldered expanders often present challenges in adaptation, chairside procedures and bond stability.
Sabina Saccomanno, Lorenzo Ederli Silenzi, Claudia Ciocia, Francesca Calò, Francesco Inchingolo, Angelo Michele Inchingolo, Grazia Marinelli, Jorida Jubani, Francesca Russo, Alessio Danilo Inchingolo, Gianna Dipalma   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Extension and compression tests mechanical behaviors of bonded granules with different bond widths

Yantu gongcheng xuebao, 2018
In order to establish a new bond failure criterion considering different bonded widths to be used in three-dimensional distinct element modelling, another three kinds of bond widths (i.e., 8, 12 and 14 mm) between granules are investigated based on the ...
JIANG Ming-jing 1,2,3, LI Chen-hui 1,2,3, LIU Wei 1,2,3, ZHANG An 1,2,3, ZHANG Xue-wen 1,2,3
doaj   +1 more source

Improving bond strength of recycled coarse aggregate concrete using chopped basalt fibers

Case Studies in Construction Materials, 2022
This paper investigates theoretically and experimentally the influence of using basalt fiber (BF) on bond strength of recycled coarse aggregate (RCA) concrete. The natural aggregate (NA) was replaced by RCA with 20 %, 40 %, 60 %, 80 %, and 100 %.
Nasim Shatarat, Hasan Katkhuda, Mohammed Ayyoub, Yasser Al-Hunaiti, Ma'en S. Abdel Jaber   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Numerical Analysis for the Progressive Failure of Binary-Medium Interface under Shearing

Advances in Civil Engineering, 2018
Binary-medium specimens were fabricated using the particle flow code, and the shear strength, dilatancy, and failure behavior of the binary-medium specimens with different bond strength ratios (0.25, 0.5, 0.75, and 1.0) under different normal stresses ...
Rihong Cao, Wenyu Tang, Hang Lin, Xiang Fan   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source