Results 61 to 70 of about 2,347,040 (191)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The effect of bond end geometry on steel – FRP joint strength

Budownictwo i Architektura, 2013
Article describes experiments on the effect of steel – FRP bond end shaping on bond strength. The influence of changing the bond end geometry on behavior of axially loaded steel elements reinforced by CFRP double patch joints with varying overlap length ...
Marek Łagoda, Maciej Kowal
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Bond Strength of composite CFRP reinforcing bars in timber [PDF]

, 2015
The use of near-surface mounted (NSM) fibre-reinforced polymer (FRP) bars is an interesting method for increasing the shear and flexural strength of existing timber members.
Luca Righetti, Antonio Borri, Borri, Antonio, Marco Corradi, Corradi, Marco, Righetti, Luca   +5 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Replacing of Internal Tension Bars by External Bonded Plate

Journal of Engineering and Sustainable Development, 2011
This paper presents comprehensive test data on the effect of replacing internal tension bars by externally bonded steel plate at beam tension face on its cracking pattern, structural deformations and ultimate strength of concrete beams reinforced with ...
Awadh E. Ajeel, Rana Hashim Ghedan, Dina Mukheef Hamza   +2 more
doaj  

Explainable ensemble learning graphical user interface for predicting rebar bond strength and failure mode in recycled coarse aggregate concrete

Developments in the Built Environment
Novel study deploys robust machine learning algorithms using newly built comprehensive dataset to predict reinforcing rebar-to-recycled coarse aggregate concrete (RCA) bond strength and failure mode.
Celal Cakiroglu, Tanvir Hassan Tusher, Md. Shahjalal, Kamrul Islam, AHM Muntasir Billah, Moncef L. Nehdi   +5 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Flexural Behavior of Concrete Beam Strengthened by Near-Surface Mounted CFRP Reinforcement Using Equivalent Section Model

Advances in Materials Science and Engineering, 2017
FRP (fiber reinforced polymer) has found wide applications as an alternative to steel rebar not only for the repair and strengthening of existing structures but also for the erection of new structures.
Woo-tai Jung, Jong-sup Park, Jae-yoon Kang, Moon-seoung Keum   +3 more
doaj   +1 more source

Texas Bond Review Board Annual Report

, 2020
This report describes states financial in fiscal 2020, issuance cost, private activity bond and 86th legislature session, This report concludes with seven appendices.
Texas Bond Review Board
core