Results 201 to 210 of about 14,136 (264)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Newly developed universal supra-nano spherical filled resin composite in posterior teeth. [PDF]

J Conserv Dent Endod
Alagha E, Alyami YD, Taibah S, El Sayed H, Habib SFK.   +4 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Validity and reliability of the Japanese version of the occupational balance questionnaire. [PDF]

Br J Occup Ther
Yamada Y, Kobayashi N, Wagman P, Håkansson C.   +3 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

A Journey Into School Lunchbox Decision-Making: A Mixed Methods Exploration of Australian Parents. [PDF]

Health Promot J Austr
Boyd W, Salehi N, Doran F, Ellis D, MCGuigan H, Lee M.   +5 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Engagement With Meditation Apps: Cross-Sectional Survey of Use and Associations. [PDF]

J Med Internet Res
Adams J, Davies J, Wattanatakulchat P, Galante J, Miller F, D'Alfonso S, Van Dam NT.   +6 more
europepmc   +1 more source

Clinical assessment of marginal and bulk fractures and discoloration in posterior composite after 12 to 36 months: A retrospective study. [PDF]

J Clin Exp Dent
Motamedosanaye V, Akbari H, Ziaaddini S, Mostafazadehbakhtiyary M, Langari AS.   +4 more
europepmc   +1 more source

A Review on the Evolution of Thermal and Environmental Barrier Coating Systems and Their High-Temperature Degradation Mechanisms in Advanced Aero-Engines. [PDF]

Materials (Basel)
Ren S, Sun Y, Yan H, Zhang X, Bao Y, Lv K.   +5 more
europepmc   +1 more source