Results 71 to 80 of about 2,349,577 (305)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Romanian Municipal Bond Market and the International Financial Crisis [PDF]

open access: yesRevista Romana de Economie, 2010
In Romania, the bond market was set up later, comparatively to the equity market. This market is in a development process, but the international financial crisis has affected even the interest of investors in bonds. The secondary municipal bond market is
VALENTINA VASILE, MIRELA MATEI
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Optimization method of investment package based on Markowitz portfolio theory

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The aim of the study is to implement and evaluate the optimization method based on the Markowitz portfolio theory. Method. The model is built using the Python programming language and the necessary libraries.
A. D. Baydalin
doaj   +1 more source

Indirect Bonding

open access: yesAustralasian Orthodontic Journal, 1994
Abstract The advantages of indirect bonding have heen recognised for more than twenty years. However the technique has not gained widespread acceptance as an alternative to conventional direct honding. Reports of difficulty in achieving adequate isolation of posterior teeth and prohlems with resin flash and low hond strength may explain ...
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Theoretical classification of corporate stocks and bonds on the current international capital market

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2005
The article deals with the theoretical classification of “classic” capital market securities, i.e. corporate stocks and bonds. Its aim was to make a detailed analysis of the individual types of these securities from the viewpoint of their main ...
Oldřich Rejnuš
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Catastrophe index-linked securities and reinsurance as substituties [PDF]

open access: yes, 2000
The use of catastrophe bonds (cat bonds) implies the problem of the so called basis risk, resulting from the fact that, in contrast to traditional reinsurance, this kind of coverage cannot be a perfect hedge for the primary’s insured portfolio.
Nell, Martin, Richter, Andreas
core  

Investment Income - Regulations in National and International Tax Legislation

open access: yesACROSS
Reasoning for the decision to invest and the role of fiscal policy objectives on the level of investment. The use of financial instruments contributes to additional revenue that can be used for the social and economic development of taxpayers in the ...
Corina BULGAC
doaj   +2 more sources

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