Results 91 to 100 of about 1,124,156 (362)
Effect of space flight on sodium, copper, manganese and magnesium content in the skeletal bones [PDF]
Sodium content decreased in the human skeletal bones and rose in the rat bones following space flight. In man copper content rose in the femoral bone and decreased in the vertebral body and the sternum, but was unchanged in the rest of the bones ...
Kolesnik, A. G.+5 more
core +1 more source
In vivo measurement of mechanical impedance of bone [PDF]
System of measurement provides indications of ulnar properties independent of characteristics of surrounding soft tissue and other bones. Mechanical modal approximated ulnar response so average bending rigidity could be determined to provide direct index
Thompson, G., Young, D. R.
core +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Ecological succession of a Jurassic shallow-water ichthyosaur fall. [PDF]
After the discovery of whale fall communities in modern oceans, it has been hypothesized that during the Mesozoic the carcasses of marine reptiles created similar habitats supporting long-lived and specialized animal communities.
A Glover+58 more
core +3 more sources
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Adipose-derived stem cells: a review of osteogenesis differentiation [PDF]
Second part of manuscript based on osteogenesis differentiation of stem cells. Bones are highly regenerative organs but there are still many problems with therapy of large bone defects.
Mazurek, Urszula+4 more
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster+3 more
wiley +1 more source
Skeletal responses to spaceflight [PDF]
The role of gravity in the determination of bone structure is elucidated by observations in adult humans and juvenile animals during spaceflight. The primary response of bone tissue to microgravity is at the interface of the mineral and matrix in the ...
Arnaud, Sara B., Morey-Holton, Emily
core +1 more source
Three-dimensional virtual bone bank system workflow for structural bone allograft selection: a technical report [PDF]
Structural bone allograft has been used in bone defect reconstruction during the last fifty years with acceptable results. However, allograft selection methods were based on 2-dimensional templates using X-rays.Thanks to preoperative planning platforms ...
Aponte Tinao, Luis+5 more
core +3 more sources
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern+7 more
wiley +1 more source