Results 111 to 120 of about 2,717,930 (384)
Ultrasonic bone densitometer [PDF]
, 1972 Human bone density changes can be determined by a device originally developed for in-flight testing of astronauts' bones during extended space missions.
Hoop, J. M.
core +1 more source
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.
Genes & Development, 1998 Osteoprotegerin (OPG) is a secreted protein that inhibits osteoclast formation. In this study the physiological role of OPG is investigated by generating OPG-deficient mice.
N. Bucay +11 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Skeletal responses to spaceflight [PDF]
The role of gravity in the determination of bone structure is elucidated by observations in adult humans and juvenile animals during spaceflight. The primary response of bone tissue to microgravity is at the interface of the mineral and matrix in the ...
Arnaud, Sara B., Morey-Holton, Emily
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Limb bone scaling in hopping diprotodonts and quadrupedal artiodactyls [PDF]
Bone adaptation is modulated by the timing, direction, rate, and magnitude of mechanical loads. To investigate whether frequent slow, or infrequent fast, gaits could dominate bone adaptation to load, we compared scaling of the limb bones from two ...
Chua, M Y +6 more
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Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Poultry Science, 2020 The application of micro-CT in small animal research, especially on bone health, has risen exponentially in recent years. However, its application in egg-laying hen bone analysis was still limited. This review introduces the technical aspects of micro-CT
C. Chen, W.K. Kim
doaj
VEGF-C promotes the development of lymphatics in bone and bone loss
eLife, 2018 Patients with Gorham-Stout disease (GSD) have lymphatic vessels in their bones and their bones gradually disappear. Here, we report that mice that overexpress VEGF-C in bone exhibit a phenotype that resembles GSD.
Devon Hominick +9 more
doaj +1 more source
Bone: Aneurysmal bone cysts [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Aneurysmal bone cysts (ABC) are benign lesions that occur more frequently in the metaphyses of long bones, especially distal femur, the proximal tibia and vertebral posterior bodies. It can occur at any age but most patients are diagnosed in the first 2 decades of life.
openaire +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source