Results 191 to 200 of about 236,194 (262)

Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment

Advanced Healthcare Materials, EarlyView.
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim, Ji Seob Kim, Min Hee Moon, Jae‐Hyeok Jang, In Sun Hwang, Byung‐Hyun Cha   +5 more
wiley   +1 more source

MicroRNA networks associated with skeletal aging and WNT pathway modulation. [PDF]

Calcif Tissue Int
Achudhan D, Monroe D, Dehankar MK, Qin L, Khosla S, Pignolo RJ, Chandra A.   +6 more
europepmc   +1 more source

POSS‐PEG‐NHS and GSH Cocrosslink DPAV to Prepare Anticalcification Bioprosthetic Scaffold With Enhanced Reendothelization, Anti‐inflammation, and Anti‐ROS

Advanced Healthcare Materials, EarlyView.
POSS‐PEG‐NHS and GSH cocrosslinked DPAV to prepare a multifunctional anticalcification valve substitute. This modification enhances mechanical properties, hemocompatibility, and re‐endothelialization while promoting anti‐inflammatory M2 macrophage infiltration and reducing calcification.
Yuqing Zhang, Chen Qian, Yingjie He, Jingli Ding, Binhao Zhang, Minghui Zou, Xing Chen, Jinping Zhao, Cuifen Lu, Jinping Liu, Jianliang Zhou   +10 more
wiley   +1 more source

Minimally Destructive Radiocarbon Dating of Bone. [PDF]

Rapid Commun Mass Spectrom
Higham T, Luftensteiner K, van der Sluis L, Giannì M, Wiegele M, Papadogianni A, Steier P, Gruber D, Schmidt B, Schmidt K, Belinski A, Mensan R, Kozlikin M, Shunkov M, Neruda P, Nerudová Z, Horejs B, Schulze J, Douka K, Stafford TW.   +19 more
europepmc   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Small bone replacement leads to greater gait asymmetry, cartilage damage, and osteophyte formation than ligament injury in a porcine wrist model. [PDF]

Osteoarthr Cartil Open
Vaughan QM, Morton AM, Moore DC, Molino J, Akelman E, Crisco JJ.   +5 more
europepmc   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Improved segmentation accuracy in high-resolution peripheral quantitative computed tomography scans of carpal bones using adaptive local thresholding. [PDF]

JBMR Plus
Kuczynski MT, Poncioni S, Elmahdy S, Baldesarra E, Zysset P, Manske SL, Whittier DE.   +6 more
europepmc   +1 more source

Clinical characteristics, advanced imaging findings, and long-term outcomes in 50 dogs with calvarial multilobular tumor of bone treated with craniectomy. [PDF]

J Vet Intern Med
Murthy VD, White LA, Rossmeisl J, Robertson JL, Kenny PJ, Chen AV, Li CF, Dickinson PJ, Vernau K, Sturges BK.   +9 more
europepmc   +1 more source

A Rare Case of Giant Cell Tumor of the First Metatarsal: En Bloc Resection and Fibular Autograft Reconstruction. [PDF]

J Orthop Case Rep
Agrawal N, Agrawal H, Verma R.
europepmc   +1 more source