Results 81 to 90 of about 2,717,930 (384)

FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease.

Genes & Development, 2002
Over the last decade the identification of mutations in the receptors for fibroblast growth factors (FGFs) has defined essential roles for FGF signaling in both endochondral and intramembranous bone development.
D. Ornitz, P. Marie
semanticscholar   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

A record of fossil shallow-water whale falls from Italy [PDF]

, 2014
Twenty-five Neogene-Quaternary whales hosted in Italian museum collections and their associated fauna were analysed for evidence of whale-fall community development in shallow-water settings.
Allison, Amano, Amano, Bellinzona, Bianucci, Bianucci, Bianucci, Bianucci, Bianucci, Bianucci, Bisconti, Bisconti, Bisconti, Borselli, Braby, Britton, Capellini, Capellini, Caretto, Carmignani, Chicchi, Coleman, Cortesi, Dahlgren, Damarco, Dando, Danise, Danise, Danise, Dominici, Dubilier, Esperante, Fergusson, Ferrero, Glover, Glover, Goedert, Goffredi, Higgs, Higgs, Hogler, Kauffman, Kiel, Kiel, Kiel, Kiel, Kubodera, Lancaster, Lundsten, Marshall, Martill, Martill, Martill, Mojetta, Naganuma, Nesbitt, Owen, Pavlyuk, Portis, Pyenson, Reisdorf, Ricci Lucchi, Richardson, Rouse, Rouse, Sahling, Sarti, Scabelli, Schäfer, Shapiro, Smith, Smith, Smith, Smith, Squires, Strobel, Tarasov, Taylor, Thorson, Trevisan, Vai, Warén   +81 more
core   +2 more sources

Remnant Woven Bone and Calcified Cartilage in Mouse Bone: Differences between Ages/Sex and Effects on Bone Strength. [PDF]

PLoS ONE, 2016
INTRODUCTION:Mouse models are used frequently to study effects of bone diseases and genetic determinates of bone strength. Murine bones have an intracortical band of woven bone that is not present in human bones.
Victoria Ip, Zacharie Toth, John Chibnall, Sarah McBride-Gagyi   +3 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Material and Structural Aspects of Bone in Osteogenesis Imperfecta [PDF]

, 2016
Bone fragility is a fundamental problem in individuals with osteogenesis imperfecta (OI). The mechanisms behind this fragility, however, are not yet well understood. Multiple factors appear to contribute to the increased fracture risk in OI.
Albert, Carolyne, Harris, Gerald F, Jameson, John, Smith, Peter   +3 more
core   +1 more source

The chondro-osseous continuum: is it possible to unlock the potential assigned within? [PDF]

, 2018
Endochondral ossification (EO), by which long bones of the axial skeleton form, is a tightly regulated process involving chondrocyte maturation with successive stages of proliferation, maturation, and hypertrophy, accompanied by cartilage matrix ...
Adams, Aizawa, Akintoye, Amling, Bahney, Ballock, Behonick, Boegård, Brachet, Cancedda, Candeliere, Carames, Clarkin, Colnot, Colnot, Day, Dodds, Emons, Enishi, Erenpreisa, Farnum, Farnum, Felson, Galotto, Gebhard, Gerstenfeld, Gibson, Gibson, Hall, Holmbeck, Hu, Hughes, Hunter, Javaheri, Jing, Johnell, Karaplis, Kawaguchi, Kuttapitiya, Lavigne, Lian, Lieu, Mackie, Maeda, Maes, Maes, Marigo, Moskalewski, Murphy, Ono, Ortega, Park, Pottenger, Poulet, Provot, Rawlinson, Riminucci, Roach, Roach, Roach, Shah, Shapiro, Silbermann, Song, Stafford, Stickens, Thesingh, Tsang, Van der Stricht, Vortkamp, Vu, Wade-Gueye, Wang, Woolf, Yang, Yoshioka, Zelzer, Zenmyo, Zhou, Zhou   +79 more
core   +3 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Craniometaphyseal and craniodiaphyseal dysplasia, head and neck manifestations and management [PDF]

, 2007
Craniometaphyseal and craniodiaphyseal dysplasia are rare genetic disorders of bone due to modelling errors of long bones and skull bones. These syndromes present with multiple ENT symptomatology from an early age.
Bailey, CM, Brain, C, Dillon, MJ, Richards, A   +3 more
core   +1 more source

Calcium phosphate crystal forms in human jaw bones of changed osteoporotic structure [PDF]

Stomatološki glasnik Srbije, 2011
Introduction. Calcium phosphates are chemical compounds that can be found in various forms within nature, as well as in human jaws and bones. The aim of this study was to assess the structure of solid chemical compounds which form the structure of ...
Poštić Srđan D.
doaj   +1 more source