Results 81 to 90 of about 109,354 (295)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Crucifixion and median neuropathy. [PDF]

, 2013
Crucifixion as a means of torture and execution was first developed in the 6th century B.C. and remained popular for over 1000 years. Details of the practice, which claimed hundreds of thousands of lives, have intrigued scholars as historical records and
Regan, Jacqueline M, Shahlaie, Kiarash, Watson, Joseph C   +2 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Development of a Co-Cr-Mo to Tantalum Transition using LENS for Orthopedic Applications [PDF]

, 2005
Biomedical implant material research using additive manufacturing is a popular field of study. Many potential material combinations exist which, if implemented properly, could have a significantly positive effect on implant life and functionality.
Kumar, Saripella Surya, Stucker, Brent
core   +1 more source

A Real-Time Dual-Microphone Speech Enhancement Algorithm Assisted by Bone Conduction Sensor

Sensors, 2020
The quality and intelligibility of the speech are usually impaired by the interference of background noise when using internet voice calls. To solve this problem in the context of wearable smart devices, this paper introduces a dual-microphone, bone ...
Yi Zhou, Yufan Chen, Yongbao Ma, Hongqing Liu   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The clinical features of the piriformis syndrome: a systematic review [PDF]

, 2010
Piriformis syndrome, sciatica caused by compression of the sciatic nerve by the piriformis muscle, has been described for over 70 years; yet, it remains controversial. The literature consists mainly of case series and narrative reviews. The objectives of
A Chantraine, A Hulbert, A Ku, A Miller, AG Filler, AH Freiberg, AH Freiberg, AJ Sutton, AM Lewis, B Gandhavadi, B Kumar, BSE Rich, C Steiner, CC Stegbauer, CE Dionne, CW Chang, CW Slipman, D Pokorny, D West, DA Jabs, DL Kent, DR Robinson, E Ernst, E Ernst, E Ernst, E Ernst, EC Papadopoulos, EC Yuen, EM Raney, ER Benson, EW Retzlaff, EY Lee, F Cramp, Fujian Song, G Waddell, GM Wyant, H Nakamura, HF Guyomarc’h, HI Pecina, HT Benzon, HW Park, I Colmegna, I Kosukegawa, IM Merlo, J Dalmau-Carola, J Karppinen, J Kouvalchouk, J Soga, J Young, JA Adams, JA Brown, JB Pace, JD Stewart, JJ Jankiewicz, JK Silver, JP Vandenbroucke, JS Kirschner, JWT Byrd, K Hopayian, K Indrekvam, K Konstantinou, Kevork Hopayian, KJ Stevens, KW Chong, L Jroundi, LF Solheim, LM Fishman, LM Fishman, LM Fishman, M Hanania, M Jenicek, M Pecina, M Tulder van, MC Vallejo, ME Julsrud, MR Foster, MR Foster, MW Cook, N Mayrand, NA Broadhurst, OA El Rubaidi, P Kobbe, P Limongelli, P Rossi, PM Barton, PM Bossuyt, R Dhote, RA Beatty, RD Karl Jr, Ricardo Riera, RJ Spinner, RL Tiel, RL Tiel, RP Beauchesne, RP Hallin, RR Richardson, S Bustamante, S Ozaki, S Turtas, SC Sayson, Sidha Sambandan, SJ Yoon, SM Papadopoulos, SM Papadopoulos, SS Hughes, T Banerjee, T Rodrigue, TN Bernard, TS Carey, V Rucco, VM Synek, VM Synek, WJ Mixter, WP Vandertop, WS Chen, WS Chen, WS Chen, Z Durrani   +117 more
core   +2 more sources

Visual Reinforcement Audiometry and Steady-State Auditory Evoked Potential in infants with and without conductive impairment

Revista CEFAC
Purpose: to compare the findings of minimum levels of answers through air and bone conductions between the Visual Reinforcement Audiometry and the Steady-State Auditory Evoked Potential in infants from six to twelve months, with and without conductive ...
Michele Vargas Garcia, Dayane Domeneghini Didoné, José Ricardo Gurgel Testa, Rúbia Soares Bruno, Marisa Frasson de Azevedo   +4 more
doaj   +1 more source