Results 191 to 200 of about 327,717 (360)

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Minimally invasive endoscopic treatment for unicameral bone cysts: technique and outcomes in a series of 33 pediatric and adolescent patients. [PDF]

J Orthop Surg Res
Zhou L, Jiang Z, Zhang Z, Yang Q, Yuan T.   +4 more
europepmc   +1 more source

Iliac bone cysts adjacent to the sacroiliac joint:an unusual cause of sacroiliac pain

, 2014
Şenol Bekmez, Mehmet Ayvaz, Musa Uğur Mermerkaya, A. Mazhar Tokgözoğlu   +3 more
openalex   +2 more sources

Pathologic fracture of the distal radius in a 25-year-old patient with a large unicameral bone cyst [PDF]

, 2014
Felix Kurt Maßen, Sebastian Felix Baumbach, Elias Volkmer, W. Mutschler, Stefan Grote   +4 more
openalex   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Multiple Treatment Analysis of Aneurysmal Bone Cysts in Mobile Spine. [PDF]

Global Spine J
Liu F, Wang B, Liu X, Wu F, Zhou H, Dang L, Li Y, Tang Y, Liu X, Hu P, Li Z, Wei F, Liu Z.   +12 more
europepmc   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Single Flexible Nailing of the Humerus for Recurrent Bone Cysts. [PDF]

J Pediatr Soc North Am
Talathi NS, Kuka CC, Arkader A.
europepmc   +1 more source

Efficacy of Percutaneous Treatment of Primary Aneurysmal Bone Cysts (ABCs): A Systematic Review and Meta-Analysis. [PDF]

J Clin Med, 2023
Samargandi R, Alkameshki M, Barnawi M, Alzahrani K, Iskander O, Nicolas Q, Hetaimish B, Berhouet J, Le Nail LR.   +8 more
europepmc   +1 more source

Bilateral aneurysmal bone cyst of the mandible: A case report

, 2015
GopalHK Sharma, A. Dabir, DeepaA Das, PreetiP Talreja-Kanchan   +3 more
openalex   +1 more source