Results 161 to 170 of about 1,814,143 (297)

An osteoporotic bone model: developing and validating an ex-vivo bone demineralization protocol. [PDF]

JBMR Plus
Alabdah F, Alshammari A, Hidalgo-Bastida A, Cooper G.   +3 more
europepmc   +1 more source

Advances in Spatial Transcriptomics in Bone. [PDF]

Curr Osteoporos Rep
Giger NV, Wehrle E.
europepmc   +1 more source

Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress

British Journal of Pharmacology, EarlyView.
Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan, Rongfang Feng, Mai Luo, Yaqi Wang, Min Gao, Qin Chen, Yufei Zhang, Yale Liu, Yumin Xia   +8 more
wiley   +1 more source

Spatial transcriptomics in bone research: navigating hype and hurdles. [PDF]

Pathology
Sokolowskei D, Shah A, Trostle AJ, Juan C, Sammarco MC, Tower RJ.   +5 more
europepmc   +1 more source

Pathology of Metastatic Tumors to Bone: Effects of Decalcification asExperienced at a Single Cancer Center

, 2016
E. Henderson-Jackson, F. Khalil
semanticscholar   +1 more source

Hypoxia Exacerbates Periapical Periodontitis‐Associated Pathological Bone Loss via the Hypoxia‐Inducible Factor‐2α‐Calmodulin‐Dependent Protein Kinase IV Axis

Cell Proliferation, EarlyView.
Hypoxia exposure activates HIF‐2α, which binds to the Camk4 promoter to enhance RANKL‐mediated osteoclast differentiation, leading to aggravated alveolar bone resorption in periapical periodontitis. ABSTRACT Periapical periodontitis is one of the most common inflammatory bone destructive diseases. Epidemiological evidence suggests that hypoxia exposure,
Kang Gao, Yifan Xu, Haoran Du, Zixiao Li, Xiaochen Fang, Minghui Wang, Jia Liu, Xu Zha, Xianglong Han, Weihua Guo, Xicheng Liu, Jian Zhou   +11 more
wiley   +1 more source

From bench to bedside: a novel suture-augmented prosthesis for greater trochanteric fixation in osteoporotic hip arthroplasty. [PDF]

J Orthop Traumatol
Yang M, Yang J, Wang X, Wu Z, Bian S, Sheng R, Liao F, Qin K, Zhang C, Yuan H, Ding X, Xie C, Ma G, Chang J.   +13 more
europepmc   +1 more source

Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation

Cell Proliferation, EarlyView.
During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu, Danning Ma, Jia Song, Boon Chin Heng, Ying Huang, Xuehui Zhang, Mingming Xu, Yan Wei, Tai Wei, Jinqi Wei, Xuliang Deng   +10 more
wiley   +1 more source

Novel Clinical Observations after Photodynamic Therapy in Choroidal Osteoma: A Three-Case Series. [PDF]

Ocul Oncol Pathol
Elizalde J, Abengoechea S, Bruix A.
europepmc   +1 more source

Unexpected Promotion of Bone Regeneration by Inhibition of BMPR1A‐Mediated BMP Signalling

Cell Proliferation, EarlyView.
BMPR1A downregulation reduces ID1, releases TCF3 to activate GNG4‐PI3K‐AKT signalling, thereby promoting OPC proliferation and bone regeneration. ABSTRACT Bone morphogenetic protein (BMP) signalling plays a pivotal role in bone regeneration by regulating osteoprogenitor cell (OPC) function, and BMPs have been widely used in clinical treatment. However,
Zihao Zhou, Yun Zhai, Xiaochen Liu, Jiaojiao Shao, Jiani Zhou, Zhaoyang Li, Jiale He, Shuxian Lin, Qi Zhang   +8 more
wiley   +1 more source