Results 61 to 70 of about 258,405 (265)

Reversible Tuning of Multiple Molecular Kinking for Stem Cell Regulation In Vivo

open access: yesAdvanced Functional Materials, EarlyView.
In this work, we introduce the novel concept of background component‐free “multiple kinks” material platform composed solely of liganded multiple kink‐bearing molecules as a strategy for dynamic biomaterial design. Tri‐kink molecules enable effective near‐infrared light‐triggered ligand masking and visible light‐triggered ligand exposure, thereby ...
Kanghyeon Kim   +28 more
wiley   +1 more source

Preferential Interfacial Engineering of Hydrogels via Interdigitated Nanoparticle Assembly

open access: yesAdvanced Functional Materials, EarlyView.
Robust surface functionalization of hydrogel surfaces is performed via interdigitated metal nanoparticle assembly, inducing strong affinity with the hydrogel matrix. The partially exposed nanoparticle domains act as interfacial nanobridges that mediate both chemical and physical bonding with diverse materials, including small molecules, fluorous ...
Hyeonjin Kim   +11 more
wiley   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu   +14 more
wiley   +1 more source

Revolutionizing bone defect healing: the power of mesenchymal stem cells as seeds

open access: yesFrontiers in Bioengineering and Biotechnology
Bone defects can arise from trauma or pathological factors, resulting in compromised bone integrity and the loss or absence of bone tissue. As we are all aware, repairing bone defects is a core problem in bone tissue engineering. While minor bone defects
Yueyao Zhang   +5 more
doaj   +1 more source

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

open access: yesAdvanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman   +9 more
wiley   +1 more source

The Genesis of Long Bone Defects Resulting from Modern Combat Trauma: Part 1. Defect Localization

open access: yesУкраїнський журнал клінічної хірургії
Objective. To characterize the pathogenesis of long bone defects resulting from modern combat trauma as a fundamental basis for developing treatment technologies and protocols for victims. Materials and Methods.
S. O. Guryev   +4 more
doaj   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

open access: yesAdvanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur   +10 more
wiley   +1 more source

An Osteoconductive, Osteoinductive, and Osteogenic Tissue-Engineered Product for Trauma and Orthopaedic Surgery: How Far Are We?

open access: yesStem Cells International, 2012
The management of large bone defects due to trauma, degenerative disease, congenital deformities, and tumor resection remains a complex issue for the orthopaedic reconstructive surgeons.
Wasim S. Khan   +3 more
doaj   +1 more source

Calvarial Bone Graft for Cranial Bone Defects

open access: yesIndian Journal of Plastic Surgery, 1996
Cranial defects are commonly a result of high velocity trauma. Bone loss may also occur as a consequence of infection or following surgical excision for tumour.
G Biswas, M K Tiwari
doaj   +1 more source

Unexpected Asymmetric Mn‐Sb Site Mixing and Reentrant Spin‐Glass State of MnSb2Te4

open access: yesAdvanced Functional Materials, EarlyView.
MnSb2Te4 is an intrinsic magnetic topological insulator. Its properties are extraordinarily sensitive to tiny defects, making structural studies essential for understanding how magnetism and topology work together. This work shows that Mn can be unevenly distributed within the crystal and how that disorder is linked to a newly reported spin‐glass state
Gustavo Chavez Ponce de Leon   +7 more
wiley   +1 more source

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