Results 141 to 150 of about 9,752 (200)

Morphological and Morphometric Analysis of Animal Hair From 18th Century Burial Sites in Mazamet (Southwest France)

Archaeometry, EarlyView.
ABSTRACT Morphological and morphometric analysis of archaeological animal hairs offers a nondestructive method to explore past clothing. We examined hair from two 18th‐century burial areas (SP03 and SP04) in Mazamet, France. SP03 specimens exhibited a continuous medulla, a low medullary index (0.2 ± 0.03) and cuticular features suggesting goat or ...
C. Michel, S. Duchesne, F. Bourgailh, F. Callede, C. H. Le Noheh, M.‐L. Merleau, D. Paya, I. Baker, F. Savall, C. Guilbeau‐Frugier   +9 more
wiley   +1 more source

Clinical efficacy analysis of mucoperiosteal flap combined with perforation technique for tooth extraction in medication-related osteonecrosis of the jaw risk population: a retrospective study. [PDF]

BMC Oral Health
Zhou Y, Li Q, Huang H, Qiao Q, Wang J, Ge N, Wang E, Zhu J, Guo Y.   +8 more
europepmc   +1 more source

The impact of scaRNA12 deregulation on p53‐mediated cellular stress response in B‐cell precursor acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Summary Small nucleolar ribonucleic acids (snoRNAs) are a class of small non‐coding RNAs involved in the post‐transcriptional modification of ribosomal RNAs (rRNA) and small nuclear RNAs (snRNA). Mounting evidence indicates that specific snoRNAs are drivers of oncogenesis, but their role in B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) is ...
Martijn W. C. Verbeek, Mathijs A. Sanders, Dwin G. B. Grashof, Remco M. Hoogenboezem, Iris van Zuijen, Annemarieke Bos, Trui van Gulck, Rosan Olsman, Rishov Mukhopadhyay, Eric M. J. Bindels, Peter J. M. Valk, Harmen J. G. van de Werken, Vincent H. J. van der Velden, Stefan J. Erkeland   +13 more
wiley   +1 more source

Beyond bone effects: the role of denosumab in muscle Health - A systematic review. [PDF]

Aging Clin Exp Res
Ceolin C, Ziliotto C, Papa MV, Bertocco A, Sergi G, De Rui M.   +5 more
europepmc   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Follow-on osteoporosis therapy after denosumab discontinuation among Medicare beneficiaries. [PDF]

Osteoporos Int
Sendhil SR, Cadarette SM, Aggarwal S, Oganisian A, Zullo AR, Berry SD, Adegboye MA, Hayes KN.   +7 more
europepmc   +1 more source

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

British Journal of Pharmacology, EarlyView.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud, Eleonora Malerba, Simona Drago, Antonella Orlando, Domenica Mallardi, Nicoletta De Lucia, Marina Antonacci, Annamaria Di Turi, Domenico Tricarico, Francesco Russo   +9 more
wiley   +1 more source

Bone density and remodeling after discontinuation of sequential therapy for premenopausal idiopathic osteoporosis. [PDF]

Osteoporos Int
Cohen A, Kamanda-Kosseh M, Rawal R, Agarwal S, Barry J, Shiau S, Colon I, Bucovsky M, Lappe JM, Shane E.   +9 more
europepmc   +1 more source

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source