Results 121 to 130 of about 10,162 (193)

Impact of sleep insufficiency and recovery on cancer development

open access: yesSleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

MXene Bioinks for 3D Bioprinting: Design and Translation

open access: yesSmall, EarlyView.
This study establishes a comprehensive framework for MXene‐based bioinks in 3D bioprinting, highlighting the interplay between rheological engineering and electroactive hydrogels. By optimizing electrical percolation and mediated signaling, these formulations drive tissue‐specific biological outcomes and accelerated regeneration.
Begüm Sarac   +2 more
wiley   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

open access: yesSmall, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung   +2 more
wiley   +1 more source

Osteoporosis therapies and coronary risk: insights from vascular calcification biology and sclerostin signaling. [PDF]

open access: yesFront Endocrinol (Lausanne)
Weng S   +7 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

open access: yesSmart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou   +4 more
wiley   +1 more source

Environmental Contaminant Accumulation in Freshwater Turtles Inhabiting Three Rivers of the Permian Basin, New Mexico, USA

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Freshwater turtles are valuable sentinels of aquatic systems due to their long lifespans and resilience in environments impacted by contaminants. The Permian Basin, dominated by the oil and gas sector, spans western Texas and southeastern New Mexico, USA, including the Pecos River and its tributaries, the Delaware and Black Rivers.
Ana G. G. Sapp   +4 more
wiley   +1 more source

Presence of Nationally Banned Carbamates and Organophosphate Pesticides in Wild Carnivores, Southeastern Brazil

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT As top predators, terrestrial carnivores face great risk of pesticide exposure and serve as sentinels of environmental contamination. Additionally, terrestrial carnivores are frequently threatened by intentional or secondary poisoning with highly toxic compounds, such as carbamates and organophosphates.
Marina Pellegrino da Silva   +10 more
wiley   +1 more source

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