Results 111 to 120 of about 5,867,531 (221)

The Anabolic-First Strategy in Osteoporosis: A Systematic Review and Meta-Analysis of Fracture Outcomes in Patients at Very High Fracture Risk. [PDF]

Medicina (Kaunas)
Cipolloni V, Bonifacio M, Hassny SM, Melara G, Lucchetti L, Gentile M, Conforti A.   +6 more
europepmc   +1 more source

Integrating ZooMS and taphonomy further highlights differential processing of animal and Neandertal carcasses in the Quina Mousterian at Les Pradelles (Marillac‐le‐Franc, southwest France)

Journal of Quaternary Science, EarlyView.
ABSTRACT The cave of Les Pradelles (Marillac‐le‐Franc, France) was repeatedly visited by Neandertals ~55 000 years ago and is a key site in discussions of Neandertal cannibalism. Excavations between 1967 and 1980 (Vandermeersch) and between 2001 and 2013 (Maureille/Mann) produced a rich faunal assemblage (>20 000 bones), alongside Quina Mousterian ...
Pauline Raymond, Jean‐Jacques Hublin, Karen Ruebens, Geoff M. Smith, Sandrine Costamagno, Cédric Beauval, Alan Mann, Bruno Maureille   +7 more
wiley   +1 more source

Bone health in advanced prostate cancer: pathophysiology and management strategies. [PDF]

Oncologist
McKay RR, Hofflich H, Woods G, Andres R, Farooki A.   +4 more
europepmc   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Revisiting the activate depress free and repeat (ADFR) paradigm: Clinical use of cyclic romosozumab. [PDF]

Arch Osteoporos
Hare K, Wheeler S, Morganti C, Krueger D, Kimmel D, Binkley N.   +5 more
europepmc   +1 more source

Tenofovir-associated bone density loss

, 2009
Iwen F Grigsby1,2,3,4,5, Lan Pham1,2,4, Louis M Mansky3,4,5, Raj Gopalakrishnan3,4, Kim C Mansky1,2,41Division of Orthodontics, 2Department of Developmental and Surgical Sciences, 3Department of Diagnostic and Biological Sciences, 4MinnCResT Program ...
Iwen F Grigsby, Lan Pham, et al, Louis M Mansky   +3 more
core  

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Denosumab increased bone mineral density but caused marked serum calcium fluctuations in a patient undergoing peritoneal dialysis. [PDF]

CEN Case Rep
Yamada S, Enomoto S, Matsuo K, Sonezaki Y, Torisu K.   +4 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Sequential Versus Step-Therapy Approaches for Osteoporosis Management in Orthopedic Subspecialties. [PDF]

Curr Osteoporos Rep
Salman SG, Phadke R, Burnett J, Walsh J.
europepmc   +1 more source