Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
Atypical femoral fracture and jaw osteonecrosis under high doses of denosumab, healed with the aid of low dose of denosumab: a case report. [PDF]
Lassoued H +3 more
europepmc +1 more source
Risk of Cancer With Hormone Replacement Therapy: A Narrative Review
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue +3 more
wiley +1 more source
An Economic and Environmental Analysis of Virtual Fencing for Precision Grazing
ABSTRACT The UK grazing livestock sector is challenged by declining farm profitability and stringent environmental policy. Innovative technologies such as virtual fencing could enable a balanced economic and environmental performance of beef production. Virtual fencing is a livestock management tool relying on invisible boundaries perceived as auditory,
Elias Maritan +4 more
wiley +1 more source
A retrospective comparative study on the effects of denosumab combined with calcium and vitamin D versus calcium and vitamin D alone on bone remodeling markers in patients with osteoporotic fractures. [PDF]
Yang Z, He P, Xu Q.
europepmc +1 more source
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu +5 more
wiley +1 more source
Revisiting Intranasal Salmon Calcitonin: Historical Osteoporosis Evidence and a Potential Role in Acute Orthopaedic Pain Management. [PDF]
Ahmad A +5 more
europepmc +1 more source
ABSTRACT In 2019, the Dadan Archaeological Project (CNRS/RCU/AFALULA) identified a Late Antique village 1 km south of ancient Dadan in the al‐ʿUlā valley (northwest Saudi Arabia). Three excavation seasons at this site (2021–2023) have uncovered a massive building constructed in the late third or early fourth cent.
Jérôme Rohmer +11 more
wiley +1 more source
Case report of severe hypocalcemia with atypical symptoms after zoledronic acid in palliative care: a deprescribing pitfall. [PDF]
Arnold T +4 more
europepmc +1 more source

