A case of severe osteomalacia secondary to phosphate diabetes in a renal transplant recipient [PDF]
, 2013 Transient hypophosphatemia is frequently observed during the first months after renal transplantation and is usually asymptomatic. Phosphate diabetes is defined as inadequate tubular phosphorus reabsorption leading to persistent renal phosphorus wasting,
D. Chappard +4 more
core +2 more sources
In vivo analysis of staphylococcus aureus-infected mice reveals differential temporal and spatial expression patterns of fhuD2 [PDF]
, 2017 Staphylococcus aureus is an opportunistic human pathogen and a major cause of invasive infections such as bacteremia, endocarditis, pneumonia and wound infections.
Bacconi, Marta +7 more
core +1 more source
Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5′ flap DNA: basis of interstrand cross-link repair by FAN1 [PDF]
, 2014 Fanconi anemia (FA) is an autosomal recessive genetic disorder caused by defects in any of 15 FA genes responsible for processing DNA interstrand cross-links (ICLs).
Carr, Antony +10 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Análisis tafonómicos de conjuntos arqueomalacológicos: concheros en la costa norte de Santa Cruz (Patagonia, Argentina) [PDF]
, 2014 En este trabajo se presenta una propuesta metodológica para el estudio de conjuntos arqueomalacológicos de concheros y su aplicación en el análisis de restos recuperados a partir de excavaciones sistemáticas en sitios ubicados al sur de la ría Deseado ...
Hammond, Heidi
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Development of flow focusing device for the visualization of leukocyte rolling adhesion [PDF]
, 2018 La microfluídica es un área de la microtecnología basada en chips de PDMS que está siendo utilizada cada vez más en multitud de aplicaciones. Una de estas aplicaciones es la investigación biomédica.
Morales Navarrete, Pablo
core
The recombinant cysteine proteinase B (CPB) from Leishmania braziliensis and its domains: promising antigens for serodiagnosis of cutaneous and visceral leishmaniasis in dogs. [PDF]
, 2019 Leishmaniasis represents a group of parasitic diseases caused by a protozoan of the genus Leishmania and is widely distributed in tropical and subtropical regions.
Basombrío, Manuel Alberto +10 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Journal of Oral Medicine and Oral SurgeryPatients often request oral rehabilitation after surgical resection. Here, a 19-year-old patient developed medication-related osteonecrosis of the jaw after treatment with antiresorptive therapy.
Salabert Noémie +3 more
doaj +1 more source