Results 11 to 20 of about 10,162 (193)

Dentists’ Awareness of Medication-Related Osteonecrosis of the Jaw (Risk Factors, Drugs, and Prevention) in the Republic of Croatia

Acta Stomatologica Croatica, 2023
Antiresorptive drugs (AR) have been used for many years in the treatment of various bone conditions such as osteoporosis, osteopenia, Paget’s disease, bone metastases, multiple myeloma and the associated malignant hypercalcemia.
Sven Bival, Lucija Šimunović, Anamarija Blažun, Lana Bergman, Domagoj Vražić, Marko Granić   +5 more
doaj   +1 more source

Analysis of the Degree of Information of Dental Surgeons about Antiresorptive Drugs According to the Time Since Graduation in Dentistry

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2023
Objective: To determine the level of scientific information of dental surgeons who carry out their professional activities in Brazil about antiresorptive drugs and indicated pharmacological procedures aiming at the prevention of osteonecrosis of the jaws
Flávia Godinho Costa Wanderley Rocha, Roberto Paulo Correia de Araújo   +1 more
doaj  

Denosumab versus zoledronic acid in cases of surgically unsalvageable giant cell tumor of bone: A randomized clinical trial

Journal of Bone Oncology, 2019
Background: Although denosumab has been approved as an antiresorptive agent for giant cell tumor of bone, its efficacy has not been proven. Objectives: To compare the efficacy and safety of denosumab and zoledronic acid treatment in patients with ...
Shenglong Li, Peng Chen, Qiankun Yang
doaj   +1 more source

Response rates for hip, femoral neck, and lumbar spine bone mineral density in patients treated with abaloparatide followed by alendronate: Results from phase 3 ACTIVExtend

Bone Reports, 2019
Abaloparatide is a selective activator of the parathyroid hormone type 1 receptor signaling pathway that favors the stimulation of bone formation. Here, we report a prospective, exploratory analysis of bone mineral density (BMD) response rates comparing ...
Chad L. Deal, Bruce H. Mitlak, Yamei Wang, Lorraine A. Fitzpatrick, Paul D. Miller   +4 more
doaj   +1 more source

Diretrizes para prevenção e tratamento da osteoporose induzida por glicocorticoide Guidelines for the prevention and treatment of glucocorticoid-induced osteoporosis

Revista Brasileira de Reumatologia, 2012
Os glicocorticoides (GC) são prescritos por praticamente todas as especialidades médicas, e cerca de 0,5% da população geral do Reino Unido utiliza esses medicamentos.
Rosa Maria Rodrigues Pereira, Jozélio Freire de Carvalho, Ana Patrícia Paula, Cristiano Zerbini, Diogo S. Domiciano, Helenice Gonçalves, Jaime S. Danowski, João F. Marques Neto, Laura M. C. Mendonça, Mailze C. Bezerra, Maria Teresa Terreri, Marta Imamura, Pedro Weingrill, Perola G. Plapler, Sebastião Radominski, Tatiana Tourinho, Vera L. Szejnfeld, Nathalia C. Andrada   +17 more
doaj   +1 more source

Fractal Dimension Analysis of Mandibular Trabecular Bone in Patients Receiving Antiresorptive Therapy for Osteoporosis and Oncologic Conditions

Diagnostics
Objectives: This study aimed to assess the effects of antiresorptive drugs on mandibular trabecular bone structure in patients with osteoporosis and those receiving antiresorptive therapy for oncologic conditions using fractal dimension (FD) analysis of ...
Mehmet Altay Sevimay, Müjde Gürsu, Muhammed Abdullah Çege, Dilek Aynur Çankal, Zühre Akarslan, Sedat Çetiner   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Bone-Targeted Therapies and Spinal Morphometry in Postmenopausal Osteoporosis: A Real-World Longitudinal Retrospective Study

Bioengineering
This 24-month retrospective, exploratory observational study evaluated longitudinal spinal morphometric changes in 128 postmenopausal women with osteoporosis receiving anabolic therapy (n = 30) or non-anabolic anti-osteoporotic therapy (n = 98).
Zhen-Wei Wu, Szu-Wei Chen, Sz-Huei Li, Wen-Tien Wu, Cheng-Huan Peng, Hao-Wen Chen, Chia-Ming Chang, Tzai-Chiu Yu, Ing-Ho Chen, Jen-Hung Wang, Kuang-Ting Yeh   +10 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source