Objectives: This study aimed to assess the effects of antiresorptive drugs on mandibular trabecular bone structure in patients with osteoporosis and those receiving antiresorptive therapy for oncologic conditions using fractal dimension (FD) analysis of ...
Mehmet Altay Sevimay+5 more
doaj +1 more source
Polysaccharide-based self-assembling nanohydrogels: An overview on 25-years research on pullulan [PDF]
The aim of this overview is to review the evolution of the studies carried out, during more than 25 years, on nanohydrogels obtained by self-assembling of pullulan (PUL) using several hydrophobization strategies.
ALHAIQUE, Franco+4 more
core +1 more source
In vivo analysis of staphylococcus aureus-infected mice reveals differential temporal and spatial expression patterns of fhuD2 [PDF]
Staphylococcus aureus is an opportunistic human pathogen and a major cause of invasive infections such as bacteremia, endocarditis, pneumonia and wound infections.
Bacconi, Marta+7 more
core +1 more source
Análisis tafonómicos de conjuntos arqueomalacológicos: concheros en la costa norte de Santa Cruz (Patagonia, Argentina) [PDF]
En este trabajo se presenta una propuesta metodológica para el estudio de conjuntos arqueomalacológicos de concheros y su aplicación en el análisis de restos recuperados a partir de excavaciones sistemáticas en sitios ubicados al sur de la ría Deseado ...
Hammond, Heidi
core
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz+5 more
wiley +1 more source
Recommendations for the optimal use of bone forming agents in osteoporosis
Bone forming agents, also known as anabolic therapies, are essential in managing osteoporosis, particularly for patients at very high-risk of fractures. Identifying candidates who will benefit the most from these treatments is crucial.
N. Veronese+23 more
semanticscholar +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Development of flow focusing device for the visualization of leukocyte rolling adhesion [PDF]
La microfluídica es un área de la microtecnología basada en chips de PDMS que está siendo utilizada cada vez más en multitud de aplicaciones. Una de estas aplicaciones es la investigación biomédica.
Morales Navarrete, Pablo
core
Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5′ flap DNA: basis of interstrand cross-link repair by FAN1 [PDF]
Fanconi anemia (FA) is an autosomal recessive genetic disorder caused by defects in any of 15 FA genes responsible for processing DNA interstrand cross-links (ICLs).
Carr, Antony+10 more
core +1 more source
The fabrication of a cellularized, multilayered 3D printed cylindrical model comprising hybrid bioinks inspired by the natural extracellular environment as an approach to artery mimetics, is presented. Using embedded bioprinting, interlayer crosslinking of self‐supporting concentric cylinders is achieved.
Uxue Aizarna‐Lopetegui+7 more
wiley +1 more source