Results 11 to 20 of about 243,671 (260)
Type 2 diabetes affects bone cells precursors and bone turnover
BMC Endocrine Disorders, 2018 Background Here we study the effect of type 2 diabetes (T2DM) on bone cell precursors, turnover and cytokines involved in the control of bone cell formation and activity. Methods We enrolled in the study 21 T2DM women and 21 non diabetic controls matched
Francesca Sassi +12 more
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BMC Musculoskeletal Disorders, 2021 Background Fragility fracture is associated with bone mineral density (BMD), and most databases used in related researches are instrument-matched.
Hong-Li Li +11 more
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Frontiers in Physiology, 2020 Adipose tissue, as the largest endocrine organ, secretes many biologically active molecules circulating in the bloodstream, collectively termed adipocytokines, which not only regulate the metabolism but also play a role in pathophysiological processes ...
Bei Guo +12 more
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Genes and Diseases, 2023 Severe insulin resistance has been linked to some of the most globally prevalent disorders, such as diabetes mellitus, nonalcoholic fatty liver disease, polycystic ovarian syndrome, and hypertension. Hereditary severe insulin resistance syndrome (H-SIRS)
Junaid Iqbal +9 more
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Antiproliferative Properties of Oleuropein in Human Osteosarcoma Cells
Natural Product Communications, 2016 In this study, we evaluated the antiproliferative activity on two human osteosarcoma cell lines (MG-63 and Saos2) of oleuropein, an olive oil compound traditionally found in the Mediterranean diet.
Jose M. Moran +6 more
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Ferroptosis and Its Potential Role in Metabolic Diseases: A Curse or Revitalization?
Frontiers in Cell and Developmental Biology, 2021 Ferroptosis is classified as an iron-dependent form of regulated cell death (RCD) attributed to the accumulation of lipid hydroperoxides and redox imbalance.
Jia-Yue Duan +13 more
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Frontiers in Endocrinology, 2022 Clinical vertebral fractures and femoral neck fractures are severe osteoporotic fractures that increase morbidity and mortality. Anthropometric variables are associated with an increased risk of osteoporotic fractures, but it is not clear whether body ...
Xi-Yu Wu +9 more
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Zoledronic acid and atorvastatin inhibit αvβ3-mediated adhesion of breast cancer cells
Journal of Bone Oncology, 2014 Bone metastases represent common long term complications of patients with breast cancer. Zoledronic acid, an amino-bisphosphonate and mevalonate pathway inhibitor, is an established agent for the treatment of bone metastases.
Maria Wilke +8 more
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Exosomes as Mediators of Cell-to-Cell Communication in Thyroid Disease
International Journal of Endocrinology, 2020 Exosomes are a type of extracellular vehicle, formed by budding cell membranes, containing proteins, DNA, and RNA. Concentrated cargoes from parent cells are enveloped in exosomes, which are cell specific and may have functions in the recipient cell ...
Yi Wang +7 more
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Exosomes and Obesity-Related Insulin Resistance
Frontiers in Cell and Developmental Biology, 2021 Exosomes are extracellular vesicles, delivering signal molecules from donor cells to recipient cells. The cargo of exosomes, including proteins, DNA and RNA, can target the recipient tissues and organs, which have an important role in disease development.
Li-Min Lei +9 more
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