Results 21 to 30 of about 243,671 (260)

Metabolic bone disease of prematurity

open access: yesJournal of Clinical & Translational Endocrinology, 2014
Metabolic bone disease (MBD) of prematurity remains a significant problem for preterm, chronically ill neonates. The definition and recommendations for screening and treatment of MBD vary in the literature. A recent American Academy of Pediatrics Consensus Statement may help close the gap in institutional variation, but evidence based practice ...
Stacy E. Rustico, MD   +2 more
openaire   +3 more sources

A novel antimicrobial peptide derived from human BPIFA1 protein protects against infection

open access: yesInnate Immunity, 2022
Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is an innate immunity defense protein. Our previous studies proved its antibacterial and antiviral effects, but its role in fungi remains unknown.
Nan Hu   +6 more
doaj   +1 more source

Role of VEGF Polymorphisms in the Susceptibility and Severity of Interstitial Lung Disease

open access: yesBiomedicines, 2021
The search for biomarkers that can help to establish an early diagnosis and prognosis of interstitial lung disease (ILD) is of potential interest. VEGF polymorphisms have been implicated in the development of several lung disorders.
Sara Remuzgo-Martínez   +18 more
doaj   +1 more source

Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo

open access: yesStem Cell Research & Therapy, 2021
Background Osteoporosis is a major public health concern for the elderly population and is characterized by fatigue load resulting in bone microdamage. The ability of bone mesenchymal stem cells (BMSCs) to repair bone microdamage diminishes with age, and
Jingqiong Xun   +8 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
(1) Background: Copper is a crucial trace element which is vital to growth and development and is especially important in bone health. Copper intake is now the focus of much broader research beyond its associations with nail growth, looking at copper’s ...
María Luz Canal-Macías   +8 more
doaj   +1 more source

Selected factors affecting bone mass in students with diagnosed obesity, aged 7–10 years, from Łódź

open access: yesPediatria i Medycyna Rodzinna, 2017
Introduction: Obesity may be a risk factor for mineralisation and bone structure disorders, contrary to a common belief in its protective effects on bone tissue. Aim: The aim of the study was to assess the relationship between selected risk factors and 
Anna Łupińska, Danuta Chlebna-Sokół
doaj   +1 more source

Underdiagnosis and underreporting of vertebral fractures on chest radiographs in men aged over 50 years or postmenopausal women with and without type 2 diabetes mellitus: a retrospective cohort study

open access: yesBMC Medical Imaging, 2022
Background Osteoporotic vertebral fractures are often clinically silent and unrecognized. The present study aimed to determine whether routine chest radiographs could be a potential screening tool for identifying missed vertebral fractures in men aged ...
Ding Na   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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