Results 51 to 60 of about 441,833 (304)

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

Vitamin D supplementation as an adjuvant therapy for patients with T2DM : an 18-month prospective interventional study [PDF]

, 2012
Background Vitamin D deficiency has been associated with impaired human insulin action, suggesting a role in the pathogenesis of diabetes mellitus type 2 (T2DM).
Al-Daghri, Nasser M., Al-Othman, Abdulaziz, Al-Saleh, Yousef, Alkharfy, Khalid M., Alokail, Majed S., Chrousos, George P., El-Kholie, Emad, Kumar, Sudhesh, Moharram, Osama, Sabico, Shaun   +9 more
core   +3 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Higher Serum Neuropeptide Y Levels Are Associated with Metabolically Unhealthy Obesity in Obese Chinese Adults: A Cross-Sectional Study

Mediators of Inflammation, 2020
Objective. Neuropeptide Y (NPY), an orexigenic peptide known to cause hyperphagia, has been involved in the occurrence and development of obesity. However, differences in the distribution of serum NPY levels in obese phenotypes (including metabolically ...
Hao-Neng Tang, Fen Xiao, Ya-Ru Chen, Si-Qi Zhuang, Yue Guo, Hui-Xuan Wu, Hou-De Zhou   +6 more
doaj   +1 more source

H19 Promotes Osteoblastic Transition by Acting as ceRNA of miR-140-5p in Vascular Smooth Muscle Cells

Frontiers in Cell and Developmental Biology, 2022
Arterial medial calcification is a common disease in patients with type 2 diabetes, end-stage renal disease and hypertension, resulting in high incidence and mortality of cardiovascular event.
Feng Xu, Jia-Yu Zhong, Bei Guo, Xiao Lin, Feng Wu, Fu-Xing-Zi Li, Su-Kang Shan, Ming-Hui Zheng, Yi Wang, Qiu-Shuang Xu, Li-Min Lei, Chang-Ming Tan, Xiao-Bo Liao, Ling-Qing Yuan   +13 more
doaj   +1 more source

Motor physiotherapy in the treatment of preterm infants with metabolic bone disease [PDF]

, 2011
OBJECTIVE: To review the role of motor physiotherapy in the treatment of preterm infants at risk of developing metabolic bone disease. DATA SOURCES: This is a review of articles published between 1986 and 2009, using the following key-words: premature ...
Fernandes, Luciana Volpiano, Guerra, Camila Campos, Moreno, Juliana   +2 more
core   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Evaluation of the Early Results of Percutaneous Ethanol Ablation in Patients with Primary Hyperparathyroidism

Acta Medica Bulgarica, 2022
Percutaneous ethanol ablation (PEA) is an alternative non-surgical method for the treatment of patients with primary hyperparathyroidism (PHPT), suitable in cases with comorbidities and high surgical risk.
Yankova I., Shinkov A., Kovatcheva R.
doaj   +1 more source

The Benefits and Concerns of Veganism in Women\u27s Health [PDF]

, 2017
There are many health benefits of consuming a vegan diet. It is associated with a decreased incidence of obesity, cardiovascular disease, type two diabetes, and a variety of cancers. Despite its numerous benefits, there are several concerns for consumers
Hester, Elisa R
core   +1 more source

Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial [PDF]

, 2015
Date of acceptance: 01/07/2015 © 2015 Witham et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
A Mahajan, Alison Avenell, AM Kamper, AT Johnston, B Iorio Di, BA Hout van, BT Workeneh, D Reaich, Deepa Sumukadas, Edmund J. Lamb, Geeta Hampson, H Roberts, I Brito-Ashurst, J Coresh, J Coresh, JA Eustace, JA Kraut, JA Kraut, JC Davis, JM Guralnik, JM Guralnik, K Baboolal, K Bibbins-Domingo, L Ceglia, LD Hughes, M Dobre, M Dobre, M Gaggl, Margaret M. Band, Marion E. T. McMurdo, ME McMurdo, ME McMurdo, Miles D. Witham, MR Wiederkehr, P Laukkanen, P Susantitaphong, Paul McNamee, PE Stevens, RB Haynes, RD Hays, Roberta C. Littleford, Roy L. Soiza, Simon A. Ogston, SJ Walters, T Rantanen, V Menon, WN Wennie Huang   +46 more
core   +4 more sources