Results 71 to 80 of about 3,945,300 (210)

Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells

open access: yesScientific Reports, 2017
Skeletal complications are common features of neonatal-onset multisystem inflammatory disease (NOMID), a disorder caused by NLRP3-activating mutations. NOMID mice in which NLRP3 is activated globally exhibit several characteristics of the human disease ...
Chun Wang   +8 more
doaj   +1 more source

Cushing’s disease and bone

open access: yesPituitary
Abstract Bone impairment associated with Cushing’s disease (CD) is a complex disorder, mainly involving deterioration of bone quality and resulting in an increased fracture rate, often despite normal bone mineral density. Bone complications are common in patients with CD at the time of diagnosis but may persist even after successful ...
Zdrojowy-Wełna, Aleksandra   +2 more
openaire   +3 more sources

Unusual appearances of benign bone cysts : Retrospective review of 452 cases.

open access: yes, 2014
This retrospective study reviewed unicameral bone cysts (UBCs) and aneurysmal cysts (ABCs) of bone with a total of 452 patients treated at Baltalimani Bone Diseases Education and Research Hospital, Turkey between 1981 and 2012.
ARIKAN, Yavuz; Baltalimani Bone Diseases Education and Research Hospital   +4 more
core   +7 more sources

Inflammatory diseases and bone fragility

open access: yes, 2017
Systemic osteoporosis and increased fracture rates have been described in chronic inflammatory diseases such as rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, inflammatory bowel diseases, and chronic obstructive pulmonary disease.
P. Geusens   +10 more
core   +1 more source

Regulation of bone mass in inflammatory diseases

open access: yes, 2022
Inflammation is among the major determinants of bone loss in chronic disease and aging. Bone metabolism is radically affected by inflammation with consequent bone loss and increased fracture risk.
Adami G, Giovanni Adami
core   +1 more source

Paget's Disease of Bone

open access: yes, 2009
Sir James Paget described the disease as follows: It begins in middle age or later, is very slow in progress, may continue for many years without influence on the general health, and may give no other trouble than those which are due to the changes of shape, size, and direction of the diseased bones (Paget 1877).
openaire   +1 more source

Fibrous Dysplasia

open access: yes, 2013
Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 8th Edition is the comprehensive revision of the field-leading reference on bone and mineral health.
Collins, Mt   +5 more
core   +1 more source

Multiscale Quantitative Imaging of Human Femoral Heads Using X-ray Microtomography [PDF]

open access: yes, 2011
PhDClinical diagnostic tools provide limited information on the underlying structural and mechanical properties of bone-tissue affected by degenerative and bone metabolic diseases.
Ahmed, Farhat
core   +2 more sources

Role and mechanism of action of Sclerostin in bone

open access: yes, 2017
After discovering that lack of Sost/sclerostin expression is the cause of the high bone mass human syndromes Van Buchem disease and sclerosteosis, extensive animal experimentation and clinical studies demonstrated that sclerostin plays a critical role in
Sato, Amy Y.   +2 more
core   +1 more source

Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo [PDF]

open access: yes, 2008
Resident macrophages are an integral component of many tissues and are important in homeostasis and repair. This study examines the contribution of resident tissue macrophages to bone physiology.
Chang, M. K.   +28 more
core   +1 more source

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