Results 61 to 70 of about 1,347,660 (311)
MicroRNA-433 Dampens Glucocorticoid Receptor Signaling, Impacting Circadian Rhythm and Osteoblastic Gene Expression [PDF]
, 2016 FUNDING This work was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health [AR44877]; the National Institutes for Dental and Craniofacial Research [5T90DE21989]; a Grant-in-Aid award ...
Delany, Anne M +4 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
SAGE Open Medical Case ReportsThis case series describes the wide spectrum of clinical presentation, laboratory findings, and morbidity/mortality associated with dengue fever in hematopoietic stem cell transplant recipients, treated in a dengue endemic region.
Waseem Shahani +11 more
doaj +1 more source
Lack of association of vitamin D receptor BsmI gene polymorphism with bone mineral density in Spanish postmenopausal women [PDF]
PeerJ, 2015 Osteoporosis is a polygenic disorder that is determined by the effects of several genes, each with relatively modest effects on bone mass. The aim of this study was to determine whether the vitamin D receptor single nucleotide polymorphism BsmI is ...
Jose M. Moran +6 more
doaj +2 more sources
Segmentation of bone structures in 3D CT images based on continuous max- ow optimization [PDF]
, 2015 In this paper an algorithm to carry out the automatic segmentation of bone structures in 3D CT images has been implemented. Automatic segmentation of bone structures is of special interest for radiologists and surgeons to analyze bone diseases or to ...
Acha Piñero, Begoña +2 more
core
Leonid Borisovich Reznik. Obituary
Остеопороз и остеопатии, 2019 The Russian Osteoporosis Association, the editors of the journal Osteoporosis and Osteopathies, regretfully report that on May 26, 2019, a famous Russian doctor, professor, doctor of medical sciences, chief freelance traumatologist of the Omsk region ...
Editorial Board Osteoporosis and Bone Diseases
doaj
Multiple verification in computational modeling of bone pathologies
, 2011 We introduce a model checking approach to diagnose the emerging of bone pathologies. The implementation of a new model of bone remodeling in PRISM has led to an interesting characterization of osteoporosis as a defective bone remodeling dynamics with ...
A. Aziz +21 more
core +2 more sources
Stem cell transplantation improves aging-related diseases [PDF]
, 2014 Aging is a complex process of damage accumulation, and has been viewed as experimentally and medically intractable. The number of patients with age-associated diseases such as type 2 diabetes mellitus (T2DM), osteoporosis, Alzheimer’s disease (AD ...
Ming Li, Susumu Ikehara
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]
, 2012 Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core +2 more sources