Results 41 to 50 of about 1,347,660 (311)

Atypically localized glomus tumor causing anterior interosseous nerve syndrome: A case report

open access: yesActa Orthopaedica et Traumatologica Turcica, 2017
This article presents a 48-year-old male patient who presented with pain in the left forearm and weakness and clumsiness in the left hand of 6 months' duration. Flexor motor strength loss of the thumb and the index finger was present and neurophysiologic
Yunus Emre Akman   +3 more
doaj   +1 more source

The Effects of Alpha Interferon on the Development of Autoimmune Thyroiditis in the NOD H2h4 Mouse

open access: yesClinical and Developmental Immunology, 2003
Alpha interferon (αIFN) therapy is known to induce thyroid autoimmunity in up to 40% of patients. The mechanism is unknown, but Th1 switching has been hypothesized.
Yael Oppenheim   +6 more
doaj   +1 more source

Measurement of abnormal bone composition in vivo using noninvasive Raman spectroscopy [PDF]

open access: yes, 2014
X-ray-based diagnostic techniques, which are by far the most widely used for diagnosing bone disorders and diseases, are largely blind to the protein component of bone.
Birch, Helen   +8 more
core   +1 more source

RAGs and Regulation of Autoantibodies [PDF]

open access: yes, 2004
Autoreactive antibodies are etiologic agents in a number of autoimmune diseases. Like all other antibodies these antibodies are produced in developing B cells by V(D)J recombination in the bone marrow.
Casellas, Rafael   +4 more
core   +1 more source

Spotted bone disease [PDF]

open access: yesBMJ Case Reports, 2015
Osteopoikilosis, a benign autosomal dominant bone disorder, is an unusual condition that can often be misdiagnosed as a sinister primary bone anomaly or as metastatic bony lesions. We report a case of osteopoikilosis in a 29-year-old Indian man. A 29-year-old unmarried man, born of non-consanguineous parents, presented with a history of low back pain ...
Riddhi, Dasgupta, Nihal, Thomas
openaire   +2 more sources

Clinical characteristics and identification of a novel TGFB1 variant in three unrelated Chinese families with Camurati‐Engelmann disease

open access: yesMolecular Genetics & Genomic Medicine, 2022
Background To investigate the clinical characteristics and molecular diagnosis of Camurati‐Engelmann disease (CAEND) in Chinese individuals. Methods We recruited six patients aged 14 to 45 years in three unrelated families with CAEND, including five ...
Xiao‐Hui Tao   +7 more
doaj   +1 more source

Development of Bone Targeting Drugs. [PDF]

open access: yes, 2017
The skeletal system, comprising bones, ligaments, cartilage and their connective tissues, is critical for the structure and support of the body. Diseases that affect the skeletal system can be difficult to treat, mainly because of the avascular cartilage
Alméciga-Díaz, Carlos J.   +6 more
core   +2 more sources

VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo. [PDF]

open access: yes, 2015
Lysosomes are classically viewed as vesicular structures to which cargos are delivered for degradation. Here, we identify a network of dynamic, tubular lysosomes that extends throughout Drosophila muscle, in vivo. Live imaging reveals that autophagosomes
Davis, Graeme W   +4 more
core   +3 more sources

Raloxifene Has No Efficacy in Reducing the High Bone Turnover and the Risk of Spontaneous Vertebral Fractures after Denosumab Discontinuation

open access: yesCase Reports in Rheumatology, 2018
At denosumab discontinuation, an antiresorptive agent is prescribed to reduce the high bone turnover, the rapid bone loss, and the risk of spontaneous vertebral fractures.
Elena Gonzalez-Rodriguez   +2 more
doaj   +1 more source

Correlation Between Low Bone Density and Disease Activity in Patients with Ulcerative Colitis [PDF]

open access: yes, 2015
BACKGROUND Different clinical and epidemiological studies using dual-energy X-ray absorptiometry have shown an increased prevalence of low bone mineral density in patients with inflammatory bowel diseases.
Aghaei, M.   +8 more
core  

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