Results 21 to 30 of about 3,945,300 (210)

The line between COVID-19 pandemic and rare bone diseases

, 2020
Rare diseases, Ostoporosis, Osteogenesis Imperfecta ...
Giovanni Adami, COVID-19 Helpline for Rare Bone Diseases Group, Sangiorgi L, Brizola E   +3 more
core   +1 more source

Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength [PDF]

, 2012
Osteoporosis is a common polygenic disease and global healthcare priority but its genetic basis remains largely unknown. We report a high-throughput multi-parameter phenotype screen to identify functionally significant skeletal phenotypes in mice ...
Gogakos Apostolos, Campbell, MJ, Anne H. van der Spek (145990), Campbell Michael J., Gogakos, A, Sunter, D, Williams, GR, David Sunter, Bassett, JHD, Boyde, A, Michael J. Campbell (5833), Sunter, D., Richard M Jacques, Project, S.M.G., Alan Boyde (146008), Croucher Peter I., Ramirez-Solis, R, Williams, G.R., Richard M. Jacques (145985), van der Spek Anne H., Holly Evans (145980), Bassett, J.H.D., Ryder, E, Edward Ryder (145998), Peter I. Croucher (146016), Graham R Williams, Evans, H, Bassett J. H. Duncan, Jacques, RM, Anne H van der Spek, J. H. Duncan Bassett (145971), Croucher, PI, Peter I Croucher, Project, SMG, Ryder, E., David Sunter (146002), Holly Evans, Gogakos, A., Jacqueline K. White (119191), Apostolos Gogakos (145975), Ramirez-Solis, R., Jacqueline K White, White Jacqueline K., Boyde, A., van der Spek, A.H., Evans, H., Michael J Campbell, Ramirez-Solis Ramiro, White, J.K., Jacques, R.M., J H Duncan Bassett, Apostolos Gogakos, Jacques Richard M., Croucher, P.I., Ryder Edward, Graham R. Williams (20148), Campbell, M.J., Evans Holly, Ramiro Ramirez-Solis (119181), Williams Graham R., Ramiro Ramirez-Solis, Edward Ryder, Alan Boyde, van der Spek, AH, Sanger Mouse Genetics Project, Sunter David, White, JK, Boyde Alan   +67 more
core   +1 more source

Paget's Disease of Bone [PDF]

New England Journal of Medicine, 1993
Paget's disease of bone may present with bone pain but is often asymptomatic. Treatment (typically with bisphosphonates) is indicated in patients with pain that is localized to an affected site but not in asymptomatic patients.
openaire   +3 more sources

Paget's disease of bone [PDF]

Postgraduate Medical Journal, 1997
SummaryPaget's disease of bone is a relatively common condition in the UK affecting up to 5% of the population over the age of 55 years with particularly high prevalence in the North West of England. The majority of those affected are asymptomatic. Its precise cause remains unknown, and until recently, choice of treatment of this sometimes painful and ...
C G, Ooi, W D, Fraser
openaire   +2 more sources

BONE–IMMUNE CELL CROSSTALK: BONE DISEASES [PDF]

, 2015
Bone diseases are associated to great morbidity, thus the understanding of the mechanisms leading to their development represent a great challenge to improve bone health.
Faccio R, D'Amelio P, Mori G, BRUNETTI, GIACOMINA, Mori, Giorgio, D’Amelio, Patrizia, Faccio, Roberta, D\u27Amelio, Patrizia, D'Amelio, Patrizia   +8 more
core   +2 more sources

Influence of cytochrome P450 and glutathione S transferase polymorphisms on response to nilotinib therapy among chronic myeloidleukemia patients from Pakistan

BMC Cancer, 2022
Background Cytochrome P450 (CYP) and glutathione S transferases (GSTs) are important biotransforming enzymes responsible for detoxification of anticancer drugs and carcinogens.
Samina Naz Mukry, Aneeta Shahni, Uzma Zaidi, Tahir Sultan Shamsi   +3 more
doaj   +1 more source

Usefulness of convalescent plasma transfusion for the treatment of severely ill COVID-19 patients in Pakistan

BMC Infectious Diseases, 2021
Background Convalescent plasma(CP) was utilized as potential therapy during COVID-19 pandemic in Pakistan. The study aimed at appraisal of CP transfusion safety and usefulness in COVID pneumonia.
Tehmina Nafees Sonia Khan, Samina Naz Mukry, Shahtaj Masood, Lubna Meraj, Bikha Ram Devrajani, Javed Akram, Naveena Fatima, Sidra Maqsood, Ayesha Mahesar, Roomana Siddiqui, Sadia Ishaque, Muhammad Bilal Afzal, Sanam Mukhtar, Sara Ahmed, Arshi Naz, Tahir Sultan Shamsi   +15 more
doaj   +1 more source

Sequencing of SARS-CoV-2 in local transmission cases through Oxford Nanopore MinION platform from Karachi Pakistan

Journal of Infection in Developing Countries, 2021
Introduction: The first case of severe acute respiratory syndrome 2 (SARS-CoV-2) was imported to Pakistan in February 2020, since then 8,260 deaths have been witnessed.
Samina Naz Mukry, Shariq Ahmed, Ali Raza Bukhari, Aneeta Shahni, Gul Sufaida, Arshi Naz, Tahir Sultan Shamsi   +6 more
doaj   +1 more source

Adipokines and Chronic Rheumatic Diseases: from Inflammation to Bone Involvement

, 2020
Besides its well-known role as energy storage tissue, adipose tissue is a biologically active tissue that can also be considered as an endocrine organ, as it is able to secrete adipokines.
Cantatore F. P., Corrado A., Colia R., Rotondo C., Cici D., Ripalta Colia, Daniela Cici, Addolorata Corrado, Cinzia Rotondo, Francesco Paolo Cantatore   +9 more
core   +1 more source

Antiproliferative Properties of Oleuropein in Human Osteosarcoma Cells

Natural Product Communications, 2016
In this study, we evaluated the antiproliferative activity on two human osteosarcoma cell lines (MG-63 and Saos2) of oleuropein, an olive oil compound traditionally found in the Mediterranean diet.
Jose M. Moran, Olga Leal-Hernandez, Maria L. Canal-Macías, Raul Roncero-Martin, Rafael Guerrero-Bonmatty, Ignacio Aliaga, Juan D. Pedrera Zamorano   +6 more
doaj   +1 more source