Results 31 to 40 of about 1,347,660 (311)

Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing [PDF]

open access: yes, 2020
Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing.
Brinkman, Antonia Clara Katharina   +10 more
core   +1 more source

Towards a New Spatial Representation of Bone Remodeling [PDF]

open access: yes, 2012
Irregular bone remodeling is associated with a number of bone diseases such as osteoporosis and multiple myeloma. Computational and mathematical modeling can aid in therapy and treatment as well as understanding fundamental biology.
Ayati, Bruce P.   +3 more
core   +2 more sources

Usefulness of convalescent plasma transfusion for the treatment of severely ill COVID-19 patients in Pakistan

open access: yesBMC Infectious Diseases, 2021
Background Convalescent plasma(CP) was utilized as potential therapy during COVID-19 pandemic in Pakistan. The study aimed at appraisal of CP transfusion safety and usefulness in COVID pneumonia.
Tehmina Nafees Sonia Khan   +15 more
doaj   +1 more source

Positioning novel biologicals in CKD-mineral and bone disorders [PDF]

open access: yes, 2017
Renal osteodystrophy (ROD), the histologic bone lesions of chronic kidney disease (CKD), is now included in a wider syndrome with laboratory abnormalities of mineral metabolism and extra-skeletal calcifications or CKD-mineral and bone disorders (CKD-MBD),
Covic, Adrian   +5 more
core   +1 more source

Sequencing of SARS-CoV-2 in local transmission cases through Oxford Nanopore MinION platform from Karachi Pakistan

open access: yesJournal of Infection in Developing Countries, 2021
Introduction: The first case of severe acute respiratory syndrome 2 (SARS-CoV-2) was imported to Pakistan in February 2020, since then 8,260 deaths have been witnessed.
Samina Naz Mukry   +6 more
doaj   +1 more source

The Assessment of the Osteoporosis Self-Assessment Tool for Asians and Calcaneal Quantitative Ultrasound in Identifying Osteoporotic Fractures and Falls Among Chinese People

open access: yesFrontiers in Endocrinology, 2021
The lack of DXA has made the diagnosis and treatment of osteoporosis extremely difficult in the vast rural areas of China, which has the largest population with high risks of osteoporosis.
Chao Gao   +4 more
doaj   +1 more source

MicroRNAs in B cell development and malignancy [PDF]

open access: yes, 2012
MicroRNAs are small RNA molecules that regulate gene expression and play critical roles in B cell development and malignancy. miRNA expression is important globally, as B cell specific knockouts of Dicer show profound defects in B cell development; and ...
Fernando, Thilini R.   +2 more
core   +4 more sources

Bone-immune cell crosstalk: Bone diseases [PDF]

open access: yes, 2015
Bone diseases are associated with great morbidity; thus, the understanding of the mechanisms leading to their development represents a great challenge to improve bone health.
Brunetti, Giacomina   +3 more
core   +5 more sources

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]

open access: yes, 2006
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra   +14 more
core   +7 more sources

Antiproliferative Properties of Oleuropein in Human Osteosarcoma Cells

open access: yesNatural Product Communications, 2016
In this study, we evaluated the antiproliferative activity on two human osteosarcoma cell lines (MG-63 and Saos2) of oleuropein, an olive oil compound traditionally found in the Mediterranean diet.
Jose M. Moran   +6 more
doaj   +1 more source

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