Results 11 to 20 of about 792,259 (266)

Osteopontin in Bone Metabolism and Bone Diseases [PDF]

open access: yesMedical Science Monitor, 2020
Osteopontin (OPN), a secreted phosphoprotein, is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of cell matrix proteins and participates in many biological activities. Studies have shown that OPN plays a role in bone metabolism and homeostasis.
Si, Jinyan   +5 more
openaire   +2 more sources

Adynamic bone disease--bone and beyond [PDF]

open access: yesClinical Kidney Journal, 2008
Disturbances of bone and mineral metabolism are a hallmark of chronic kidney disease (CKD). Renal osteodystrophy (ROD) is the traditional term for bone lesions in conjunction with CKD and is now considered a part of the ‘chronic kidney disease—mineral and bone disorder’ (CKD-MBD) [1].
Brandenburg, Vincent M., Floege, Jürgen
openaire   +2 more sources

Autoinflammatory Bone Diseases. [PDF]

open access: yesBalkan Med J
Autoinflammatory bone diseases (AIBDs) constitute a recently identified subset of autoinflammatory diseases. These conditions are characterized by an exaggerated inflammatory response in the bones without any apparent etiology. Inflammatory bone lesions associated with AIBDs exhibit chronic inflammation, are typically culture-negative, and do not ...
Haşlak F   +6 more
europepmc   +5 more sources

Parkinson’s disease and the bones

open access: yesSwiss Medical Weekly, 2011
PRINCIPLES: Bone and joint problems in Parkinson’s disease (PD) are manifold: decreased mobility, abnormal posture, as well as the risk of falling may cause both acute and chronic damage to the musculoskeletal system. In patients with Parkinson’s disease, postural instability and falls are frequently observed.
Gnädinger, M   +2 more
openaire   +4 more sources

Paget's disease of bone [PDF]

open access: yesThe Journal of Bone and Joint Surgery. British volume, 1979
This chapter focuses on Paget's disease of bone. The pathological hallmark of the Paget's bone disease is excessive and disorganized activity of bone that involves both matrix and mineral. There is no idea of its cause and little knowledge of its natural history; however, the biochemical changes produced by the overactive bone justify its inclusion as ...
openaire   +3 more sources

Clinical Characteristics of Primary Hyperparathyroidism: 15-Year Experience of 457 Patients in a Single Center in China

open access: yesFrontiers in Endocrinology, 2021
ObjectivePrimary hyperparathyroidism (PHPT) is a common endocrine disorder of calcium metabolism. However, data concerning a large cohort of PHPT patients in the Chinese population are scarce.
Xiaoyun Lin   +3 more
doaj   +1 more source

Paget's Disease of Bone [PDF]

open access: yesNew England Journal of Medicine, 1993
Paget's disease of bone may present with bone pain but is often asymptomatic. Treatment (typically with bisphosphonates) is indicated in patients with pain that is localized to an affected site but not in asymptomatic patients.
openaire   +3 more sources

Effect of BMI on outcomes of surgical treatment for tibial plateau fractures: A comparative retrospective case series study

open access: yesChinese Journal of Traumatology, 2018
Purpose: Tibia plateau fracture (TPF) treatment aims at achieving a stable, aligned, mobile, painless knee and preventing post-traumatic osteoarthritis. To achieve this goal, surgeons consider criteria such as patients' characteristics, severity, risk of
Yaşar Mahsut Dinçel   +5 more
doaj   +1 more source

Influence of cytochrome P450 and glutathione S transferase polymorphisms on response to nilotinib therapy among chronic myeloidleukemia patients from Pakistan

open access: yesBMC Cancer, 2022
Background Cytochrome P450 (CYP) and glutathione S transferases (GSTs) are important biotransforming enzymes responsible for detoxification of anticancer drugs and carcinogens.
Samina Naz Mukry   +3 more
doaj   +1 more source

Usefulness of convalescent plasma transfusion for the treatment of severely ill COVID-19 patients in Pakistan

open access: yesBMC Infectious Diseases, 2021
Background Convalescent plasma(CP) was utilized as potential therapy during COVID-19 pandemic in Pakistan. The study aimed at appraisal of CP transfusion safety and usefulness in COVID pneumonia.
Tehmina Nafees Sonia Khan   +15 more
doaj   +1 more source

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