Results 131 to 140 of about 281,009 (311)

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: A drill-hole defect model

, 2011
Objective: To establish a drill-hole defect model in osteoporotic mouse femur by comparing temporal cortical bone healing pattern between OVX-induced osteoporotic bone and sham-operated bone.
Lei Wei, Zhang, Ge, Li, Gang, Leung, Kwok-Sui, Zheng, Li-Zhen, Hung, Leung-Kim, Leung-Kim Hung, Cao, Yong-Ping, Ling Qin, Yi-Xin He, Ge Zhang, Xiao-Hua Pan, Wei, Lei, Kwong-Man Lee, Chun-Wai Chan, Yong-Ping Cao, Qin, Ling, He, Yi-Xin, Li-zhen Zheng, Liu, Zhong, Pan, Xiao-Hua, Lee, Kwong-Man, Gang Li, Kwok-Sui Leung, Chan, Chun-Wai, Zhong Liu   +25 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Chitosan nanofiber scaffold improves bone healing via stimulating trabecular bone production due to upregulation of the Runx2/osteocalcin/alkaline phosphatase signaling pathway

, 2015
Ming-Hua Ho,1,2 Chih-Jung Yao,3 Mei-Hsiu Liao,4 Pei-I Lin,4 Shing-Hwa Liu,5 Ruei-Ming Chen2,4,6 1Department of Chemical Engineering, National Taiwan University of Science and Technology, 2Cell Physiology and Molecular Image Research Center, Taipei ...
Liao MH, Liu SH, Lin PI, Chen RM, Yao CJ, Ho MH   +5 more
core  

Early mechanical stimulation only permits timely bone healing in sheep

, 2017
Bone fracture healing is sensitive to the fixation stability. However, it is unclear which phases of healing are mechano-sensitive and if mechanical stimulation is required throughout repair.
Shanker, Mihir, Pelin Tufekci, Steck, Roland, Neumann, Mirjam V., Michael Schuetz, Devakar Epari, Dlaska, Constantin Edmond, Saifzadeh, Siamak, Aramesh Tavakoli, Mirjam Neumann, Tavakoli, Aramesh, Epari, Devakara R., Schuetz, Michael, Siamak Saifzadeh, Tufekci, Pelin Melisa, Roland Steck, Constantin Dlaska, Mihir Shanker   +17 more
core   +1 more source

Mechanisms of tendon-bone interface healing: biomechanics, cell mechanics, and tissue engineering approaches

Journal of Orthopaedic Surgery and Research
The healing of tendon-bone contact surfaces involves complex biomechanical and biochemical interactions, with pivotal implications for sports medicine and rehabilitation.
Zhixiong Xu, Wensheng Xu, Tao Zhang, Long Luo   +3 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

The design, manufacture and analysis of a new implant for fracture fixation in human and veterinary orthopaedic surgery: the bone fastenerod [PDF]

, 2002
Fracture fixation in humans and animals has troubled surgeons and scientists since first it was attempted right up to the present day. At every milestone of achievement in the understanding and practice of fracture repair there has remained a significant
McCartney, William T.
core  

Size and Habit of Mineral Particles in Bone and Mineralized Callus During Bone Healing in Sheep

, 2010
Bone healing is known to occur through the successive formation and resorption of various tissues with different structural and mechanical properties.
Manjubala, Inderchand, Manjubala, I., Liu, Yifei, Duda, Georg N, Roschger, Paul, Epari, D. R., Liu, Y., Fratzl, P., Schell, H., Duda, G., Epari, Devakara R., Liu, Y. F., Schell, Hanna, Fratzl, Peter, Epari, D., Roschger, P., Duda, G. N.   +16 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source