Results 1 to 10 of about 33,351 (233)

External stimulation: A potential therapeutic strategy for tendon-bone healing [PDF]

Frontiers in Bioengineering and Biotechnology, 2023
Injuries at the tendon-bone interface are very common in the field of sports medicine, and healing at the tendon-bone interface is complex. Injuries to the tendon-bone interface can seriously affect a patient’s quality of life, so it is essential to ...
Shijie Fu, Shijie Fu, Shijie Fu, Yujian Lan, Guoyou Wang, Dingsu Bao, Bo Qin, Qiu Zheng, Huan Liu, Vincent Kam Wai Wong   +9 more
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Strategies for promoting tendon-bone healing: Current status and prospects [PDF]

Frontiers in Bioengineering and Biotechnology, 2023
Tendon-bone insertion (TBI) injuries are common, primarily involving the rotator cuff (RC) and anterior cruciate ligament (ACL). At present, repair surgery and reconstructive surgery are the main treatments, and the main factor determining the curative ...
Chenhui Yang, Chenhui Yang, Chenhui Yang, Chenhui Yang, Yuanjun Teng, Yuanjun Teng, Yuanjun Teng, Bin Geng, Bin Geng, Bin Geng, Hefang Xiao, Hefang Xiao, Hefang Xiao, Changshun Chen, Changshun Chen, Changshun Chen, Rongjin Chen, Rongjin Chen, Rongjin Chen, Fei Yang, Fei Yang, Fei Yang, Yayi Xia, Yayi Xia, Yayi Xia   +24 more
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Challenges in tendon–bone healing: emphasizing inflammatory modulation mechanisms and treatment [PDF]

Frontiers in Endocrinology
Tendons are fibrous connective tissues that transmit force from muscles to bones. Despite their ability to withstand various loads, tendons are susceptible to significant damage.
Fan Jiang, Haibo Zhao, Po Zhang, Yanchi Bi, Haoyun Zhang, Shenjie Sun, Yizhi Yao, Xuesai Zhu, Fenghua Yang, Yang Liu, Sicong Xu, Tengbo Yu, Xiao Xiao   +12 more
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Mechanisms and new advances in the efficacy of plant active ingredients in tendon-bone healing [PDF]

Journal of Orthopaedic Surgery and Research
The tendon-bone interface, known as the tenosynovial union or attachment, can be easily damaged by excessive exercise or trauma. Tendon-bone healing is a significant research topic in orthopedics, encompassing various aspects of sports injuries and ...
Yuan Li, Wei Wang, Wensheng Xu
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Therapeutic Potential of Exosomes in Tendon and Tendon–Bone Healing: A Systematic Review of Preclinical Studies [PDF]

Journal of Functional Biomaterials, 2023
Exosomes have been proven to play a positive role in tendon and tendon–bone healing. Here, we systematically review the literature to evaluate the efficacy of exosomes in tendon and tendon–bone healing.
Mingrui Zou, Jingzhou Wang, Zhenxing Shao   +2 more
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Regulating Macrophages through Immunomodulatory Biomaterials Is a Promising Strategy for Promoting Tendon-Bone Healing

Journal of Functional Biomaterials, 2022
The tendon-to-bone interface is a special structure connecting the tendon and bone and is crucial for mechanical load transfer between dissimilar tissues.
Haihan Gao, Liren Wang, Haocheng Jin, Zhiqi Lin, Ziyun Li, Yuhao Kang, Yangbao Lyu, Wenqian Dong, Yefeng Liu, Dingyi Shi, Jia Jiang, Jinzhong Zhao   +11 more
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Strategies to promote tendon-bone healing after anterior cruciate ligament reconstruction: Present and future

Frontiers in Bioengineering and Biotechnology, 2023
At present, anterior cruciate ligament (ACL) reconstruction still has a high failure rate. Tendon graft and bone tunnel surface angiogenesis and bony ingrowth are the main physiological processes of tendon-bone healing, and also the main reasons for the ...
Bin Tian, Ming Zhang, Xin Kang
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Didymin may Enhance Tendon‐Bone Healing Partly by Promoting PPAR‐Mediated Fatty Acid Oxidation and Macrophage M2 Polarization [PDF]

Immunity, Inflammation and Disease
Objective Achieving rapid and high‐quality regeneration after injury at the tendon‐bone interface remains an urgent challenge in the fields of orthopedics, sports medicine, and tissue regeneration.
Xiaojun Ma, Jia Shen, Jun Ma, Hangyu Li, Yang Li, Jun Wan   +5 more
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Macrophage polarisation under immune regulation as a therapeutic target for tendon-bone healing: multifactorial regulation and mechanistic insights [PDF]

Frontiers in Immunology
Recovery from a variety of surgical treatments, including arthroscopic rotator cuff repair and anterior cruciate ligament restoration, depends heavily on tendon-bone healing.
Wanxue Wang, Liang Zhang, Yu Jiang, Dexi Cui, Kehao Hou, Shengquan Ren, Xia Zhao, Yingze Zhang, Ning Yu, Chao Qi, Kuishuai Xu   +10 more
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Bioactive siRNA‐Based Liposomes Promoted Tendon‐Bone Healing in Osteoporotic Mice by Recovering the Stemness of CD248+ TSPCs [PDF]

Advanced Science
Osteoporosis significantly impairs tendon‐bone healing, increasing the risk of rotator cuff tears and postoperative retearing. Tendon stem/progenitor cells (TSPCs) are vital for tendon repair, with their stemness crucial to healing outcomes.
Yinhua Qian, Jinguo Zhu, Yanwei He, Haocheng Qin, Pingkang Qian, Bingfeng Sun, Haoqiang Huang, Chen Kuang, Quan Yang, Yuxi Ou, Rong Sun, Feng Xu, Xianwen Wang, Zhiwen Luo, Qing Wang   +14 more
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