Results 21 to 30 of about 33,351 (233)

Solid-Liquid Interface Lubricating Hydrogels for Tendon-Bone Healing. [PDF]

Research (Wash D C)
A solid-liquid interface lubrication system composed of tissue and synovial fluid ensures the physiological functions of the tendon-bone (TB). However, after the TB tears, stress concentration and friction disrupt the solid-liquid interface lubrication of the TB and disturb its healing.
Zhuang P, Chen L, Zhang Y, Yang W, Chen Y, Wu L, Xiang L, Wang Z, Rosenholm JM, Zuo G, Ye T, Zhang H, Cui W.   +12 more
europepmc   +3 more sources

Stem cell therapies in tendon-bone healing

World Journal of Stem Cells, 2021
Tendon-bone insertion injuries such as rotator cuff and anterior cruciate ligament injuries are currently highly common and severe. The key method of treating this kind of injury is the reconstruction operation. The success of this reconstructive process depends on the ability of the graft to incorporate into the bone.
Xu, Yue, Zhang, Wan-Xia, Wang, Li-Na, Ming, Yue-Qing, Li, Yu-Lin, Ni, Guo-Xin   +5 more
openaire   +2 more sources

Amorphous calcium phosphate nanoparticles using adenosine triphosphate as an organic phosphorus source for promoting tendon–bone healing

Journal of Nanobiotechnology, 2021
Background Rotator cuff tear (RCT) is a common problem of the musculoskeletal system. With the advantage of promoting bone formation, calcium phosphate materials have been widely used to augment tendon-bone healing.
Haoran Liao, Han-Ping Yu, Wei Song, Guangcheng Zhang, Bingqiang Lu, Ying-Jie Zhu, Weilin Yu, Yaohua He   +7 more
doaj   +1 more source

Immobilization Modulates Macrophage Accumulation in Tendon-Bone Healing [PDF]

Clinical Orthopaedics & Related Research, 2009
Tendon-to-bone healing occurs by formation of a fibrous, scar tissue interface rather than regeneration of a normal insertion. Because inflammatory cells such as macrophages lead to formation of fibrous scar tissue, we hypothesized immobilization would allow resolution of acute inflammation and result in improved tendon-bone healing.
Elias, Dagher, Peyton L, Hays, Sumito, Kawamura, Jon, Godin, Xiang-hua, Deng, Scott A, Rodeo   +5 more
openaire   +2 more sources

Biology and augmentation of tendon-bone insertion repair

Journal of Orthopaedic Surgery and Research, 2010
Surgical reattachment of tendon and bone such as in rotator cuff repair, patellar-patella tendon repair and anterior cruciate ligament (ACL) reconstruction often fails due to the failure of regeneration of the specialized tissue ("enthesis") which ...
Lui PPY, Zhang P, Chan KM, Qin L
doaj   +1 more source

Delivery of GAS5 by LNP promotes tendon-bone healing in rotator cuff injury. [PDF]

Bioact Mater
It is observed in clinical practice that worse healing in rotator cuff tear (RCT) is closely associated with osteoporosis in patients. Herein, from the statistical analysis, we further confirmed that the RCT is significantly increased in postmenopausal women who suffer from decreased bone mineral density (BMD), suggesting intervention of osteoporosis ...
Li M, Li X, He Z, Luo Y, Yao Z, Hou J, Yan Y, Long Y, Chen Y, Yang R.   +9 more
europepmc   +4 more sources

Effect of treadmill training on fibrocartilage complex repair in tendon-bone insertion healing in the postinflammatory stage

Bone & Joint Research, 2023
Aims: Mechanical stimulation is a key factor in the development and healing of tendon-bone insertion. Treadmill training is an important rehabilitation treatment.
Jindong Tan, Xiao Liu, Mei Zhou, Feng Wang, Lin Ma, Hong Tang, Gang He, Xia Kang, Xuting Bian, Kanglai Tang   +9 more
doaj   +1 more source

The Effect of Cyclooxygenase Inhibition on Tendon‐Bone Healing in an In Vitro Coculture Model [PDF]

Mediators of Inflammation, 2015
The effects of cyclooxygenase (COX) inhibition following the reconstruction of the anterior cruciate ligament remain unclear. We examined the effects of selective COX‐2 and nonselective COX inhibition on bone‐tendon integration in an in vitro model. We measured the dose‐dependent effects of ibuprofen and parecoxib on the viability of lipopolysaccharide‐
Tim Schwarting, Sebastian Pretzsch, Florian Debus, Steffen Ruchholtz, Philipp Lechler   +4 more
openaire   +3 more sources

Graft healing in anterior cruciate ligament reconstruction

Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology, 2009
Successful anterior cruciate ligament reconstruction with a tendon graft necessitates solid healing of the tendon graft in the bone tunnel. Improvement of graft healing to bone is crucial for facilitating an early and aggressive rehabilitation and ...
Chen Chih-Hwa
doaj   +1 more source

Biological fixation in anterior cruciate ligament surgery

Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, 2014
Successful anterior cruciate ligament (ACL) reconstruction with tendon graft requires extensive tendon-to-bone healing in the bone tunnels and progressive graft ligamentization for biological, structural, and functional recovery of the ACL.
Chih-Hwa Chen, Chian-Her Lee
doaj   +1 more source