VEGF with AMD3100 Endogenously Mobilizes Mesenchymal Stem Cells and Improves Fracture Healing [PDF]
, 2018 A significant number of fractures develop non‐union. Mesenchymal stem cell (MSC) therapy may be beneficial, however, this requires cell acquisition, culture and delivery. Endogenous mobilization of stem cells offers a non‐invasive alternative.
Blunn, G +3 more
core +3 more sources
Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength [PDF]
, 2014 Experimental studies suggest that the β‐blocker propranolol stimulates bone formation but little work has investigated its effect on fracture healing. In this study, we examined if a low dose of propranolol, previously shown to be preventive against bone
Apel +39 more
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Bone fracture healing in mechanobiological modeling: A review of principles and methods
Bone Reports, 2017 Bone fracture is a very common body injury. The healing process is physiologically complex, involving both biological and mechanical aspects. Following a fracture, cell migration, cell/tissue differentiation, tissue synthesis, and cytokine and growth ...
Mohammad S. Ghiasi +4 more
doaj +1 more source
An approximate model for cancellous bone screw fixation [PDF]
, 2013 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Taylor & Francis.This paper presents a finite element (FE) model to identify parameters that affect the performance of an improved ...
A. Day +31 more
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Comparative histological and histomorphometric results of six biomaterials used in two-stage maxillary sinus augmentation model after 6-month healing [PDF]
, 2018 To evaluate the performances of six different bone substitute materials used as graft in maxillary sinus augmentation by means of histological and histomorphometric analysis of bone biopsies retrieved from human subjects after a 6-month healing period ...
Cristalli, MARIA PAOLA +5 more
core +1 more source
Methods for evaluation of early bone healing at titanium implants [PDF]
, 2007 Titanium has for a long time been the implant material of choice when in need for abilities as strength, biocompatibility and stability. Although numbers of studies have been made, little is known about the early events in implant healing.
Hederstierna, Karin
core +1 more source
A Longitudinal Low Dose μCT Analysis of Bone Healing in Mice: A Pilot Study
Advances in Orthopedics, 2014 Low dose microcomputed tomography (μCT) is a recently matured technique that enables the study of longitudinal bone healing and the testing of experimental treatments for bone repair.
Lu-Zhao Di +9 more
doaj +1 more source
Dysfunctional stem and progenitor cells impair fracture healing with age [PDF]
, 2019 Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new vasculature that supplies ...
Clauss, Matthias +12 more
core +1 more source
Immune modulation as a therapeutic strategy in bone regeneration
Journal of Experimental Orthopaedics, 2015 We summarize research approaches and findings on bone healing and regeneration that were presented at a workshop at the 60th annual meeting of the Orthopedic Research Society (ORS) in New Orleans in 2014.
Claudia Schlundt +5 more
doaj +1 more source
Clinical Cases in Mineral and Bone Metabolism, 2016 Delayed fracture healing and nonunion occurs in up to 5-10% of all fractures, and can present a challenging clinical scenario for the treating physician. Methods for the enhancement of skeletal repair may benefit patients that are at risk of, or have experienced, delayed healing or nonunion.
John A, Buza, Thomas, Einhorn
openaire +2 more sources