Age-related changes to macrophages are detrimental to fracture healing in mice. [PDF]
, 2020 The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age ...
Brazina, Sloane +8 more
core +2 more sources
External stimulation: A potential therapeutic strategy for tendon-bone healing
Frontiers in Bioengineering and Biotechnology, 2023 Injuries at the tendon-bone interface are very common in the field of sports medicine, and healing at the tendon-bone interface is complex. Injuries to the tendon-bone interface can seriously affect a patient’s quality of life, so it is essential to ...
Shijie Fu +9 more
doaj +1 more source
Bone & Joint Research, 2020 Aims Cigarette smoking has a negative impact on the skeletal system, causes a decrease in bone mass in both young and old patients, and is considered a risk factor for the development of osteoporosis. In addition, it disturbs the bone healing process and
Chao-Jui Chang +4 more
semanticscholar +1 more source
Impaired bone healing at tooth extraction sites in CD24-deficient mice: A pilot study. [PDF]
PLoS ONE, 2018 To use a micro-computed tomography (micro-CT) to quantify bone healing at maxillary first molar extraction sites, and test the hypothesis that bone healing is impaired in CD24-knockout mice as compared with wild-type C57BL/6J mice.Under ketamine-xylazine
Limor Avivi-Arber +4 more
doaj +1 more source
Dental Research Journal, 2021 Background: Nitric oxide (NO) has several functions in bone healing and affects bone metabolism. Selective inducible NO synthase (iNOS) inhibitors can be used to assess the efficacy of NO for healing of bone defects. This study sought to assess the local
Ali Reza Farhad +4 more
doaj +1 more source
L-configuration re-attachment of distal biceps tendon rupture [PDF]
, 2009 In distal biceps tendon ruptures, re-attachment to the radial tuberosity should ensure adequate tendon to bone contact for optimal ...
Charalambous, CP +4 more
core +2 more sources
In silico Mechano-Chemical Model of Bone Healing for the Regeneration of Critical Defects: The Effect of BMP-2. [PDF]
PLoS ONE, 2015 The healing of bone defects is a challenge for both tissue engineering and modern orthopaedics. This problem has been addressed through the study of scaffold constructs combined with mechanoregulatory theories, disregarding the influence of chemical ...
Frederico O Ribeiro +4 more
doaj +1 more source
VEGF with AMD3100 Endogenously Mobilizes Mesenchymal Stem Cells and Improves Fracture Healing [PDF]
, 2018 A significant number of fractures develop non‐union. Mesenchymal stem cell (MSC) therapy may be beneficial, however, this requires cell acquisition, culture and delivery. Endogenous mobilization of stem cells offers a non‐invasive alternative.
Blunn, G +3 more
core +3 more sources
Bone healing in extraction sockets covered with collagen membrane alone or associated with porcine-derived bone graft: a comparative histological and histomorphometric analysis [PDF]
, 2017 The present paper reports data of a randomized study aimed to analyse and compare the histologic and histomorphometric aspects of bone healing in extraction sites covered with collagen membrane alone or associated with porcine-derived bone ...
De Angelis, Francesca +6 more
core +2 more sources
Bone fracture healing in mechanobiological modeling: A review of principles and methods
Bone Reports, 2017 Bone fracture is a very common body injury. The healing process is physiologically complex, involving both biological and mechanical aspects. Following a fracture, cell migration, cell/tissue differentiation, tissue synthesis, and cytokine and growth ...
Mohammad S. Ghiasi +4 more
doaj +1 more source