Results 41 to 50 of about 19,246 (265)

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Modulation of the Inflammatory Response and Bone Healing

Frontiers in Endocrinology, 2020
The optimal treatment for complex fractures and large bone defects is an important unsolved issue in orthopedics and related specialties. Approximately 5–10% of fractures fail to heal and develop non-unions.
Masahiro Maruyama, Claire Rhee, Takeshi Utsunomiya, Ning Zhang, Masaya Ueno, Zhenyu Yao, Stuart B. Goodman, Stuart B. Goodman   +7 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The Biology of Bone and Ligament Healing [PDF]

Foot and Ankle Clinics, 2016
This review describes the normal healing process for bone, ligaments, and tendons, including primary and secondary healing as well as bone-to-bone fusion. It depicts the important mediators and cell types involved in the inflammatory, reparative, and remodeling stages of each healing process.
Treena Livingston Arinzeh, Jessica Cottrell, Jessica Cardenas Turner, J. Patrick O'Connor   +3 more
openaire   +3 more sources

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Mesenchymal stem cells and macrophages and their interactions in tendon-bone healing

Journal of Orthopaedic Translation, 2023
Tendon-bone insertion injuries (TBI), such as anterior cruciate ligament (ACL) and rotator cuff injuries, are common degenerative or traumatic pathologies with a negative impact on the patient's daily life, and they cause huge economic losses every year.
Zhuo Chen, Mingchao Jin, Hongyi He, Jiabao Dong, Jing Li, Jiangbo Nie, Zichen Wang, Juntao Xu, Fengfeng Wu   +8 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Mechanisms and new advances in the efficacy of plant active ingredients in tendon-bone healing

Journal of Orthopaedic Surgery and Research
The tendon-bone interface, known as the tenosynovial union or attachment, can be easily damaged by excessive exercise or trauma. Tendon-bone healing is a significant research topic in orthopedics, encompassing various aspects of sports injuries and ...
Yuan Li, Wei Wang, Wensheng Xu
doaj   +1 more source

The progress in quantitative evaluation of callus during distraction osteogenesis

BMC Musculoskeletal Disorders, 2022
The manual monitoring of callus with digital radiography (X-ray) is the primary bone healing evaluation, assessing the number of bridged callus formations. However, this method is subjective and nonquantitative.
Qi Liu, Ze Liu, Hongbin Guo, Jieyu Liang, Yi Zhang   +4 more
doaj   +1 more source

A 3D in Silico Multi-Tissue Evolution Model Highlights the Relevance of Local Strain Accumulation in Bone Fracture Remodeling

Frontiers in Bioengineering and Biotechnology, 2022
Since 5–10% of all bone fractures result in non-healing situations, a thorough understanding of the various bone fracture healing phases is necessary to propose adequate therapeutic strategies.
Camille Perier-Metz, Camille Perier-Metz, Laurent Corté, Laurent Corté, Rachele Allena, Sara Checa   +5 more
doaj   +1 more source